50-131-33
CD328 (Siglec7) Monoclonal Antibody (eBioQA79 (QA79)), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-131-33-Each-of-1 | In Stock | ₹ 12,549.00 |
50-131-33 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,549.00
GST (18%): ₹ 2,258.82
Total Price: ₹ 14,807.82
Antigen
CD328 (Siglec7)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9Y286
Gene Symbols
SIGLEC7
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27036
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunoprecipitation
Clone
eBioQA79 (QA79)
Conjugate
Unconjugated
Gene
SIGLEC7
Gene Alias
Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Description
- Description: The eBioQA79 monoclonal antibody reacts with adhesion inhibitory receptor molecule 1 (AIRM1), also known as sialic acid binding immunoglobulin-like lectin 7 (Siglec-7), p75 and CDw328
- AIRM1 is a cell surface receptor that belongs to the sialoadhesin family and displays homology with the myeloid cell antigen CD33
- p75/AIRM1 expression is confined to NK cells in lymphoid cells
- eBioQA79 crosslinking inhibits NK function
- p75/AIRM1 is expressed at various stages of myeloid differentiation
- Presence of this protein is a useful way to monitor cellular proliferation and determine proliferative states of cells, especially in diseases such as chronic myeloid leukemia
- Applications Reported: This eBioQA79 (QA79) antibody has been reported for use in flow cytometric analysis, and immunoprecipitation
- Applications Tested: This eBioQA79 (QA79) antibody has been tested by flow cytometric analysis
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- Putative adhesion molecule that mediates sialic-acid dependent binding to cells
- Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid
- Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide)
- The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
- In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules
- Mediates inhibition of natural killer cells cytotoxicity
- May play a role in hemopoiesis
- Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Compare Similar Items
Show Difference
Antigen: CD328 (Siglec7)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9Y286
Gene Symbols: SIGLEC7
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27036
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunoprecipitation
Clone: eBioQA79 (QA79)
Conjugate: Unconjugated
Gene: SIGLEC7
Gene Alias: Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD328 (Siglec7)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9Y286
Gene Symbols:
SIGLEC7
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27036
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunoprecipitation
Clone:
eBioQA79 (QA79)
Conjugate:
Unconjugated
Gene:
SIGLEC7
Gene Alias:
Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: Nanog
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q80Z64
Gene Symbols: NANOG
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 71950
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: eBioMLC-51
Conjugate: Unconjugated
Gene: NANOG
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Nanog
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q80Z64
Gene Symbols:
NANOG
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
71950
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
eBioMLC-51
Conjugate:
Unconjugated
Gene:
NANOG
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Nanog
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9H9S0
Gene Symbols: NANOG
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79923
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: hNanog.2
Conjugate: Unconjugated
Gene: NANOG
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Nanog
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9H9S0
Gene Symbols:
NANOG
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79923
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
hNanog.2
Conjugate:
Unconjugated
Gene:
NANOG
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Nanog
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9H9S0
Gene Symbols: NANOG
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79923
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: hNanog.2
Conjugate: Unconjugated
Gene: NANOG
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Nanog
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9H9S0
Gene Symbols:
NANOG
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79923
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
hNanog.2
Conjugate:
Unconjugated
Gene:
NANOG
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ