50-132-57
CD314 (NKG2D) Monoclonal Antibody (5C6), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-132-57-Each-of-1 | In Stock | ₹ 21,475.56 |
50-132-57 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,475.56
GST (18%): ₹ 3,865.601
Total Price: ₹ 25,341.161
Antigen
CD314 (NKG2D)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P26718
Gene Symbols
Klrk1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22914
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Neutralization
Clone
5C6
Conjugate
Unconjugated
Gene
Klrk1
Gene Alias
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Description
- Description: The 5C6 monoclonal antibody reacts with the human NKG2D, a 42 kDa lectin-like molecule expressed by NK cells, gammadelta T cells, some CD4^+ and CD8^+ T cells
- Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors
- The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma
- 5C6 and 1D11 block binding of soluble MICA to gammadelta TCR T cell clones and inhibit lysis by these cells
- 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells
- Applications Reported: The 5C6 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistochemical staining
- It has also been reported in inhibition of ligand binding in in vitro assays
- Please use Functional Grade purified 5C6, cat
- 16-5879, in functional assays.)
- Applications Tested: The 5C6 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation
- NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function
- The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain
- The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
Compare Similar Items
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Antigen: CD314 (NKG2D)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P26718
Gene Symbols: Klrk1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22914
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Neutralization
Clone: 5C6
Conjugate: Unconjugated
Gene: Klrk1
Gene Alias: CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
CD314 (NKG2D)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P26718
Gene Symbols:
Klrk1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22914
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation, Neutralization
Clone:
5C6
Conjugate:
Unconjugated
Gene:
Klrk1
Gene Alias:
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: Dendritic Cell Marker DCIR2
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: 0
Gene Symbols: Clec4a4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 474145
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone: 33D1
Conjugate: Unconjugated
Gene: Clec4a4
Gene Alias: Clec4a4; C-type lectin domain family 4, member a4; DC Marker; Dcir2; dendritic cell inhibitory receptor 2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Dendritic Cell Marker DCIR2
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
0
Gene Symbols:
Clec4a4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
474145
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone:
33D1
Conjugate:
Unconjugated
Gene:
Clec4a4
Gene Alias:
Clec4a4; C-type lectin domain family 4, member a4; DC Marker; Dcir2; dendritic cell inhibitory receptor 2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: Ly-49H
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q60682
Gene Symbols: Klra8
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16639
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunoprecipitation
Clone: 3D10
Conjugate: Unconjugated
Gene: Klra8
Gene Alias: Cmv1; Cmv-1; cytomegalovirus resistance 1; killer cell lectin-like receptor 8; killer cell lectin-like receptor, subfamily A, member 8; Klra8; Ly49H; Ly-49h; Ly49-h; Ly49u<129>; Lymphocyte antigen 49h; T-cell surface glycoprotein Ly-49H
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Ly-49H
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q60682
Gene Symbols:
Klra8
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16639
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation
Clone:
3D10
Conjugate:
Unconjugated
Gene:
Klra8
Gene Alias:
Cmv1; Cmv-1; cytomegalovirus resistance 1; killer cell lectin-like receptor 8; killer cell lectin-like receptor, subfamily A, member 8; Klra8; Ly49H; Ly-49h; Ly49-h; Ly49u<129>; Lymphocyte antigen 49h; T-cell surface glycoprotein Ly-49H
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Integrin alpha 4 beta 7 (LPAM-1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P26011, Q00651
Gene Symbols: Itga4, Itgb7
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16401, 16421
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay
Clone: DATK32 (DATK-32)
Conjugate: Unconjugated
Gene: Itgb7
Gene Alias: CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Integrin alpha 4 beta 7 (LPAM-1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P26011, Q00651
Gene Symbols:
Itga4, Itgb7
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16401, 16421
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay
Clone:
DATK32 (DATK-32)
Conjugate:
Unconjugated
Gene:
Itgb7
Gene Alias:
CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ