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50-146-43

NK1.1 Monoclonal Antibody (PK136), Functional Grade, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size	SKU	Availability	Price
Each of 1	50-146-43-Each-of-1	In Stock	₹ 29,518.20

50-146-43 - Each of 1

₹ 29,518.20

In Stock

Quantity

Base Price: ₹ 29,518.20

GST (18%): ₹ 5,313.276

Total Price: ₹ 34,831.476

Antigen

NK1.1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

P27812, P27814

Gene Symbols

Klrb1b, Klrb1c

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17059, 80782

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Functional Assay

Clone

PK136

Conjugate

Functional Grade

Gene

Klrb1c

Gene Alias

AI462337; CD161; CD161 antigen-like family member B; CD161 antigen-like family member C; CD161b; CD161c; EMBL:AAQ11375.1}; Inhibitory receptor NKR-P1B; killer cell lectin-like receptor subfamily A member 1C; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; KLRB1; Klrb1b; klrb1b {ECO:0000312; Klrb1c; Klrb1d; Klrb1f; klrb1f {ECO:0000250; Ly55; Ly-55; Ly55b; ly-55b; Ly55c; ly-55c; Ly55d; Ly-55d; Ly59; Ly-59; lymphocyte antigen 55 complex, locus B; lymphocyte antigen 55 complex, locus C; lymphocyte antigen 55 complex, locus D; lymphocyte antigen 55b; lymphocyte antigen 55c; Lymphocyte antigen 55d; lymphocyte antigen 59; MGC163757; MGC163759; natural killer cell receptor protein NKR-P1B; natural killer cell receptor protein NKR-P1C; natural killer cell receptor-P1; natural killer cell surface protein NKR-P1B allele B6; Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344; natural killer cell surface protein NKR-P1B allele SJL/BALB; natural killer cell surface protein NKR-P1B allele TO; natural killer cell surface protein NKR-P1F; Natural killer cell surface protein P1-40; natural killer cell-associated antigen 1; natural killer cells; nk cells; Nk1; Nk-1; NK1.1; Nk1.2; Nk-1.2; NKRP1; NK-RP1; NKR-P1 34; NKR-P1 40; NKR-P1.9; NKRP140; Nkrp1b; NKR-P1B; Nkrp1-b; NKR-P1B protein; Nkrp1c; NKR-P1C; Nkrp1d; NKR-P1D; Nkrp1f; NKR-P1F; RGD:2975}; UniProtKB:Q8VD98}

Host Species

Mouse

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Description

Description: The PK136 monoclonal antibody reacts with mouse NK1.1, an antigen expressed by natural killer cells and a subset of T cells in the NK1.1 mouse strains including C57BL and NZB
Several commonly used laboratory mouse strains such as BALB/c, SJL, AKR, CBA, C3H and A do not express the NK1.1 antigen
For detection of NK cells in these strains the monoclonal antibody DX5 (Cat
No
14-5971) should be used
Simultaneous staining of C57BL/6 spleen cells with PK136 and DX5 reveals coexpression of both markers by a majority of cells as well as presence of small populations of DX5+PK136- and DX5-PK136+ cells
Applications Reported: PK136 has been reported for use in flow cytometric analysis, depletion of NK cells, and in vitro functional studies
Applications Tested: The PK136 antibody has been tested by flow cytometric analysis of C57Bl/6 mouse splenocytes and can be used at less than or equal to 0.5 μg per test
A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
It is recommended that the antibody be carefully titrated for optimal performance in other applications
Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay
Storage and handling: Use in a sterile environment
Filtration: 0.2 μm post-manufacturing filtered
NK1.1 (Killer cell lectin-like receptor subfamily B, member 1, KLRB1, NKR-P1A, CD161, cluster of differentiation 161), refers to Natural Killer (NK) cells, lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation
Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function
The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain
The KLRB1 protein, NKR-P1A or CD161, is classified as a type II membrane protein because it has an external C terminus
NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand.

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Fischer Scientific

50-146-43

Antigen:

NK1.1

Classification:

Monoclonal

Concentration:

1 mg/mL

Formulation:

PBS with no preservative; pH 7.2

Gene Accession No.:

P27812, P27814

Gene Symbols:

Klrb1b, Klrb1c

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

17059, 80782

Content And Storage:

4° C

Form:

Liquid

Applications:

Flow Cytometry, Functional Assay

Clone:

PK136

Conjugate:

Functional Grade

Gene:

Klrb1c

Gene Alias:

AI462337; CD161; CD161 antigen-like family member B; CD161 antigen-like family member C; CD161b; CD161c; EMBL:AAQ11375.1}; Inhibitory receptor NKR-P1B; killer cell lectin-like receptor subfamily A member 1C; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; KLRB1; Klrb1b; klrb1b {ECO:0000312; Klrb1c; Klrb1d; Klrb1f; klrb1f {ECO:0000250; Ly55; Ly-55; Ly55b; ly-55b; Ly55c; ly-55c; Ly55d; Ly-55d; Ly59; Ly-59; lymphocyte antigen 55 complex, locus B; lymphocyte antigen 55 complex, locus C; lymphocyte antigen 55 complex, locus D; lymphocyte antigen 55b; lymphocyte antigen 55c; Lymphocyte antigen 55d; lymphocyte antigen 59; MGC163757; MGC163759; natural killer cell receptor protein NKR-P1B; natural killer cell receptor protein NKR-P1C; natural killer cell receptor-P1; natural killer cell surface protein NKR-P1B allele B6; Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344; natural killer cell surface protein NKR-P1B allele SJL/BALB; natural killer cell surface protein NKR-P1B allele TO; natural killer cell surface protein NKR-P1F; Natural killer cell surface protein P1-40; natural killer cell-associated antigen 1; natural killer cells; nk cells; Nk1; Nk-1; NK1.1; Nk1.2; Nk-1.2; NKRP1; NK-RP1; NKR-P1 34; NKR-P1 40; NKR-P1.9; NKRP140; Nkrp1b; NKR-P1B; Nkrp1-b; NKR-P1B protein; Nkrp1c; NKR-P1C; Nkrp1d; NKR-P1D; Nkrp1f; NKR-P1F; RGD:2975}; UniProtKB:Q8VD98}

Host Species:

Mouse

Quantity:

500 μg

Primary or Secondary:

Primary

Target Species:

Mouse

Product Type:

Antibody

Isotype:

IgG2a κ

Invitrogen

50-146-44

Antigen:

IFNAR1

Classification:

Monoclonal

Concentration:

1 mg/mL

Formulation:

PBS with no preservative; pH 7.2

Gene Accession No.:

P33896

Gene Symbols:

Ifnar1

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

15975

Content And Storage:

4° C

Form:

Liquid

Applications:

Functional Assay, Neutralization

Clone:

MAR1-5A3

Conjugate:

Functional Grade

Gene:

Ifnar1

Gene Alias:

alpha-type antiviral protein; AVP; beta-type antiviral protein; CD118; CRF2-1; cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; H3K1; Ifar; IFN R1; IFNalpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFNalpha/betaR1; IFN-alpha/betaR1; IFN-alpha/betaRalpha; IFNalpha/beta-Ralpha; IFN-alpha-REC; IFNAR; Ifnar1; IFNBR; IFNR1; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha and beta receptor subunit 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1

Host Species:

Mouse

Quantity:

500 μg

Primary or Secondary:

Primary

Target Species:

Mouse

Product Type:

Antibody

Isotype:

IgG1 κ

eMolecules

50-146-4488

Antigen:

Classification:

Concentration:

Formulation:

Gene Accession No.:

Gene Symbols:

Purification Method:

Regulatory Status:

Gene ID (Entrez):

Content And Storage:

Form:

Applications:

Clone:

Conjugate:

Gene:

Gene Alias:

Host Species:

Quantity:

Primary or Secondary:

Target Species:

Product Type:

Isotype:

Invitrogen

50-146-45

Antigen:

B7-H4

Classification:

Monoclonal

Concentration:

1 mg/mL

Formulation:

PBS with no preservative; pH 7.2

Gene Accession No.:

Q7Z7D3

Gene Symbols:

Vtcn1

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

79679

Content And Storage:

4° C

Form:

Liquid

Applications:

Control, Flow Cytometry, Functional Assay

Clone:

H74

Conjugate:

Functional Grade

Gene:

Vtcn1

Gene Alias:

B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312

Host Species:

Mouse

Quantity:

100 μg

Primary or Secondary:

Primary

Target Species:

Human

Product Type:

Antibody

Isotype:

IgG1 κ

NK1.1 Monoclonal Antibody (PK136), Functional Grade, eBioscience™, Invitrogen™

Select a Size

Select a Size

Properties

Antigen

Classification

Concentration

Formulation

Gene Accession No.

Gene Symbols

Purification Method

Regulatory Status

Gene ID (Entrez)

Content And Storage

Form

Applications

Clone

Conjugate

Gene

Gene Alias

Host Species

Quantity

Primary or Secondary

Target Species

Product Type

Isotype

Description

Compare Similar Items

Show Difference

Fischer Scientific

Invitrogen

eMolecules​

Invitrogen

eMolecules