50-155-7043

PELP1/MNAR Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-7043-Each-of-1 In Stock ₹ 41,863.65

50-155-7043 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

PELP1/MNAR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PELP1

Gene Alias

HMX3, MNAR, P160, modulator of non-genomic activity of estrogen receptor; modulator of nongenomic activity of estrogen receptor; proline and glutamic acid rich nuclear protein; proline, glutamic acid and leucine rich protein 1; proline-, glutamic acid- and leucine-rich protein 1; proline-, glutamic acid-, leucine-rich protein 1; transcription factor HMX3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27043, 75273

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q8IZL8, Q9DBD5

Gene Symbols

Pelp1

Immunogen

Between 1000 and 1050

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence- specific transcription factors
  • Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner
  • Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol
  • Plays a role in E2-mediated cell cycle progression by interacting with RB1
  • May have important functional implications in ER/growth factor cross-talk
  • Interacts with several growth factor signaling components including EGFR and HRS
  • Involved in nuclear receptor signaling via its interaction with AR and NR3C1
  • May promote tumorigenesis via its interaction with and modulation of several oncogenes including SRC, PI3K, STAT3 and EGFR
  • Plays a role in cancer cell metastasis via its ability to modulate E2-mediated cytoskeleton changes and cell migration via its interaction with SRC and PI3K
  • Functions as the key stabilizing component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-7043

--


Antigen:
PELP1/MNAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PELP1

Gene Alias:
HMX3, MNAR, P160, modulator of non-genomic activity of estrogen receptor; modulator of nongenomic activity of estrogen receptor; proline and glutamic acid rich nuclear protein; proline, glutamic acid and leucine rich protein 1; proline-, glutamic acid- and leucine-rich protein 1; proline-, glutamic acid-, leucine-rich protein 1; transcription factor HMX3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27043, 75273

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q8IZL8, Q9DBD5

Gene Symbols:
Pelp1

Immunogen:
Between 1000 and 1050

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7051

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Antigen:
QKI

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
QKI

Gene Alias:
Protein quaking; HqkI; Hqk; QKI; HKQ

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19317, 9444

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q96PU8, Q9QYS9

Gene Symbols:
Qk, QKI

Immunogen:
C-terminus of isoform 5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7054

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Antigen:
Rad50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD50

Gene Alias:
NBSLD, RAD50-2, hRad50

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10111

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q92878

Gene Symbols:
RAD50

Immunogen:
Between 50 and 100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7057

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Antigen:
Rad50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD50

Gene Alias:
NBSLD, RAD50-2, hRad50

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10111

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q92878

Gene Symbols:
RAD50

Immunogen:
Between 700 and 750

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG