50-155-7379
PHD2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7379-Each-of-1 | In Stock | ₹ 11,905.67 |
50-155-7379 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,905.67
GST (18%): ₹ 2,143.021
Total Price: ₹ 14,048.691
Antigen
PHD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EGLN1
Gene Alias
C1ORF12, Chromosome 1 Open Reading Frame 12, EGL 9 homolog of C. elegans 1, EGLN 1 EGLN1, HIF Prolyl Hydroxylase 2, HIF-P4H 2, HIFPH2, P4H2, Prolyl Hy
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54583
Content And Storage
4° C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q9GZT9
Gene Symbols
EGLN1
Immunogen
Between 1 and 50
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- HIF prolyl hydroxylase 2 is a prolyl hydroxylase that modifies HIF-alpha
- Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the HPH sites do not resemble those modifying collagen
- HIF is a transcriptional complex that plays a critical role in oxygen homeostasis
- HPH is an essential component of the pathway through which cells sense oxygen
- In the presence of oxygen, HPHs convert specific prolyl residues in HIF-alpha to hydroxyproline, leading to HIF-alpha destruction
- Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF is stable and there is increased angiogenesis
- HPH-2, specifically, catalyzes the posttranslational formation of 4-hydroxyproline in HIF alpha proteins
- It hydroxylates HIF-1 alpha at Pro(402) and Pro(564), and HIF-2 alpha
- It targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex.
Compare Similar Items
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Antigen: PHD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EGLN1
Gene Alias: C1ORF12, Chromosome 1 Open Reading Frame 12, EGL 9 homolog of C. elegans 1, EGLN 1 EGLN1, HIF Prolyl Hydroxylase 2, HIF-P4H 2, HIFPH2, P4H2, Prolyl Hy
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54583
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9GZT9
Gene Symbols: EGLN1
Immunogen: Between 1 and 50
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EGLN1
Gene Alias:
C1ORF12, Chromosome 1 Open Reading Frame 12, EGL 9 homolog of C. elegans 1, EGLN 1 EGLN1, HIF Prolyl Hydroxylase 2, HIF-P4H 2, HIFPH2, P4H2, Prolyl Hy
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54583
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9GZT9
Gene Symbols:
EGLN1
Immunogen:
Between 1 and 50
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PHD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EGLN3
Gene Alias: EGL9 homolog of C. elegans 3, EGLN3, Factor responsive smooth muscle protein, HIF Prolyl Hydroxylase 3, HIFP4H3, HIFPH3, P4H3, Prolyl Hydroxylase Doma
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 112399, 112407
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q91UZ4, Q9H6Z9
Gene Symbols: Egln3
Immunogen: Between 50 and 100
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PHD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EGLN3
Gene Alias:
EGL9 homolog of C. elegans 3, EGLN3, Factor responsive smooth muscle protein, HIF Prolyl Hydroxylase 3, HIFP4H3, HIFPH3, P4H3, Prolyl Hydroxylase Doma
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
112399, 112407
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q91UZ4, Q9H6Z9
Gene Symbols:
Egln3
Immunogen:
Between 50 and 100
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PHD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4HTM
Gene Alias: EGLN4, HIF Prolyl Hydroxylase 4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54681
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9NXG6
Gene Symbols: P4HTM
Immunogen: Between 450 and C-term
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4HTM
Gene Alias:
EGLN4, HIF Prolyl Hydroxylase 4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54681
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9NXG6
Gene Symbols:
P4HTM
Immunogen:
Between 450 and C-term
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PHD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4HTM
Gene Alias: EGLN4, HIF Prolyl Hydroxylase 4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54681
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q9NXG6
Gene Symbols: P4HTM
Immunogen: Between 450 and C-term
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4HTM
Gene Alias:
EGLN4, HIF Prolyl Hydroxylase 4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54681
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q9NXG6
Gene Symbols:
P4HTM
Immunogen:
Between 450 and C-term
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG