50-155-7380
PHD3 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7380-Each-of-1 | In Stock | ₹ 41,863.65 |
50-155-7380 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
PHD3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EGLN3
Gene Alias
EGL9 homolog of C. elegans 3, EGLN3, Factor responsive smooth muscle protein, HIF Prolyl Hydroxylase 3, HIFP4H3, HIFPH3, P4H3, Prolyl Hydroxylase Doma
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
112399, 112407
Content And Storage
4° C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q91UZ4, Q9H6Z9
Gene Symbols
Egln3
Immunogen
Between 50 and 100
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- HIF prolyl hydroxylase 3 is a prolyl hydroxylase that modifies HIF-alpha
- Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the HPH sites do not resemble those modifying collagen
- HIF is a transcriptional complex that plays a critical role in oxygen homeostasis
- HPH is an essential component of the pathway through which cells sense oxygen
- In the presence of oxygen, HPHs convert specific prolyl residues in HIF-alpha to hydroxyproline, leading to HIF-alpha destruction
- Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF is stable and there is increased angiogenesis
- HIF prolyl hydroxylase 1, specifically, catalyzes the posttranslational formation of 4-hydroxyproline in HIF alpha proteins
- It hydroxylates HIF-1 alpha at Pro(564) and HIF-2 alpha
- It targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex
- It may also play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissues, promoting cell death through a caspase-dependent mechanism.
Compare Similar Items
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Antigen: PHD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EGLN3
Gene Alias: EGL9 homolog of C. elegans 3, EGLN3, Factor responsive smooth muscle protein, HIF Prolyl Hydroxylase 3, HIFP4H3, HIFPH3, P4H3, Prolyl Hydroxylase Doma
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 112399, 112407
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q91UZ4, Q9H6Z9
Gene Symbols: Egln3
Immunogen: Between 50 and 100
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PHD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EGLN3
Gene Alias:
EGL9 homolog of C. elegans 3, EGLN3, Factor responsive smooth muscle protein, HIF Prolyl Hydroxylase 3, HIFP4H3, HIFPH3, P4H3, Prolyl Hydroxylase Doma
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
112399, 112407
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q91UZ4, Q9H6Z9
Gene Symbols:
Egln3
Immunogen:
Between 50 and 100
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PHD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4HTM
Gene Alias: EGLN4, HIF Prolyl Hydroxylase 4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54681
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9NXG6
Gene Symbols: P4HTM
Immunogen: Between 450 and C-term
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4HTM
Gene Alias:
EGLN4, HIF Prolyl Hydroxylase 4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54681
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9NXG6
Gene Symbols:
P4HTM
Immunogen:
Between 450 and C-term
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PHD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P4HTM
Gene Alias: EGLN4, HIF Prolyl Hydroxylase 4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54681
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q9NXG6
Gene Symbols: P4HTM
Immunogen: Between 450 and C-term
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PHD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
P4HTM
Gene Alias:
EGLN4, HIF Prolyl Hydroxylase 4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54681
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q9NXG6
Gene Symbols:
P4HTM
Immunogen:
Between 450 and C-term
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CoAA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBM14
Gene Alias: COAA, PSP2, SIP, SYTIP1, TMEM137, RNA-binding protein 14, RRM-containing coactivator activator/modulator, SYT-interacting protein, paraspeckle protein 2, synaptotagmin-interacting protein, transmembrane protein 137
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10432
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q96PK6
Gene Symbols: RBM14
Immunogen: Between 150 and 200
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CoAA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBM14
Gene Alias:
COAA, PSP2, SIP, SYTIP1, TMEM137, RNA-binding protein 14, RRM-containing coactivator activator/modulator, SYT-interacting protein, paraspeckle protein 2, synaptotagmin-interacting protein, transmembrane protein 137
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10432
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q96PK6
Gene Symbols:
RBM14
Immunogen:
Between 150 and 200
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG