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50-155-9900

ABRO Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-9900-Each-of-1 In Stock ₹ 43,546.81

50-155-9900 - Each of 1

₹ 43,546.81

In Stock

Quantity

1

Base Price: ₹ 43,546.81

GST (18%): ₹ 7,838.426

Total Price: ₹ 51,385.236

Antigen

ABRO

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ABRAXAS2

Gene Alias

Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23172

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.2 mg/ml

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q15018

Gene Symbols

ABRAXAS2

Immunogen

Between 350 and 390

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Component of the BRISC complex, a multiprotein complex that specifically cleaves ′Lys-63′-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates (PubMed:19214193, PubMed:20032457, PubMed:20656690, PubMed:24075985)
  • May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (PubMed:20656690)
  • Plays a role in regulating the onset of apoptosis via its role in modulating ′Lys-63′-linked ubiquitination of target proteins
  • Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665)
  • Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097)
  • Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985)
  • Required for normal induction of p53/TP53 in response to DNA damage (PubMed:25283148)
  • Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (PubMed:25283148).

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Img

Bethyl Laboratories, Inc

50-155-9900

--

Antigen:
ABRO
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABRAXAS2
Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23172
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q15018
Gene Symbols:
ABRAXAS2
Immunogen:
Between 350 and 390
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9902

--

Antigen:
ABRO
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABRAXAS2
Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23172
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q15018
Gene Symbols:
ABRAXAS2
Immunogen:
Between 350 and 390
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9903

--

Antigen:
ABRO
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABRAXAS2
Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23172
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q15018
Gene Symbols:
ABRAXAS2
Immunogen:
Between 390 and 415
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9904

--

Antigen:
ABRO
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABRAXAS2
Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23172
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q15018
Gene Symbols:
ABRAXAS2
Immunogen:
Between 390 and 415
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG