50-156-0342
DFF45/DFFA Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-0342-Each-of-1 | In Stock | ₹ 41,863.65 |
50-156-0342 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
DFF45/DFFA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DFFA
Gene Alias
DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1676
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
0.2 mg/ml
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
O00273
Gene Symbols
DFFA
Immunogen
Between 271 and 331
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- ICAD is the inhibitor of caspase-3-activated DNase which is a substrate that controls nuclear apoptosis
- ICAD has two isoforms: a functional isoform of 45kDa, ICAD-L/DNA fragmentation factor (DFF) 45; and a 35kDa isoform, ICAD-S/DFF35
- Although both ICAD-L and ICAD-S can bind and inhibit CAD, only ICAD-L was reported to be functional
- ICAD is cleaved to be inactivated and allow caspase-activated DNase (CAD) to execute nuclear internucleosomal apoptotic DNA fragmentation
- In non-apoptotic cells, CAD is complexed with its inhibitor, ICAD
- The activation of the CAD/ICAD complex occurs through the caspase 3-mediated cleavage of ICAD at residues 117 and 224, which results in three ICAD fragments that are then released from CAD
- In addition to its DNase inhibitory activity, ICAD acts as a CAD specific folding chaperone
- There are recent reports that ICAD is a potential target for restoring a normal apoptotic signal transduction pathway in colon and brain cancer cells
- Two alternatively spliced transcript variants encoding distinct isoforms have been found for the ICAD gene.
Compare Similar Items
Show Difference
Antigen: DFF45/DFFA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DFFA
Gene Alias: DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1676
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O00273
Gene Symbols: DFFA
Immunogen: Between 271 and 331
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DFF45/DFFA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DFFA
Gene Alias:
DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1676
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O00273
Gene Symbols:
DFFA
Immunogen:
Between 271 and 331
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DFF45/DFFA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DFFA
Gene Alias: DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1676
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O00273
Gene Symbols: DFFA
Immunogen: Between 271 and 331
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DFF45/DFFA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DFFA
Gene Alias:
DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1676
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O00273
Gene Symbols:
DFFA
Immunogen:
Between 271 and 331
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DFF35/DFFA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DFFA
Gene Alias: DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1676
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O00273
Gene Symbols: DFFA
Immunogen: C-terminus
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DFF35/DFFA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DFFA
Gene Alias:
DFF, ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, ICAD
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1676
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O00273
Gene Symbols:
DFFA
Immunogen:
C-terminus
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SART1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SART1
Gene Alias: SART1; squamous cell carcinoma antigen recognised by T cells; ARA1; Ara1; HOMS1; MGC2038; SART1259; Snu66; IgE autoantigen; SART1(259) protein; SART1(800) protein; U4/U6.U5 tri-snRNP-associated 110 kDa protein; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells 1; SNRNP110; small nuclear ribonucleoprotein 110kDa (U4/U6.U5)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9092
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: O43290
Gene Symbols: SART1
Immunogen: Between 675 and 725
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SART1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SART1
Gene Alias:
SART1; squamous cell carcinoma antigen recognised by T cells; ARA1; Ara1; HOMS1; MGC2038; SART1259; Snu66; IgE autoantigen; SART1(259) protein; SART1(800) protein; U4/U6.U5 tri-snRNP-associated 110 kDa protein; squamous cell carcinoma antigen recognised by T cells; squamous cell carcinoma antigen recognized by T cells 1; SNRNP110; small nuclear ribonucleoprotein 110kDa (U4/U6.U5)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9092
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
O43290
Gene Symbols:
SART1
Immunogen:
Between 675 and 725
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG