50-156-1968

SPHK1 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-1968-Each-of-1 In Stock ₹ 11,905.67

50-156-1968 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

SPHK1

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q9NYA1

Gene Symbols

SPHK1

Immunogen

Between 334 and 384

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

SPHK1

Gene Alias

RP23-193A16.4, 1110006G24Rik, Sk1, Spk1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8877

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Sphingosine Kinase (SphK) catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P)
  • S1P subsequently signals through cell surface G protein-coupled receptors, as well as intracellularly, to modulate cell proliferation, survival, motility and differentiation
  • SphK is an important signaling enzyme which is activated by diverse agents, including growth factors that signal through receptor tyrosine kinases, agents activating G protein-coupled receptors, and immunoglobulin receptors
  • Two SphK isotypes, SphK-1 and SphK-2, have been cloned, and both isotypes are ubiquitously expressed
  • SphK-1 has been shown to mediate cell growth, prevention of apoptosis, and cellular transformation, and is upregulated in a variety of human tumors
  • In contrast, SphK-2 increases apoptosis, and may be responsible for phosphorylating and activating the immunosuppressive drug FTY720.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-156-1968

--


Antigen:
SPHK1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9NYA1

Gene Symbols:
SPHK1

Immunogen:
Between 334 and 384

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
SPHK1

Gene Alias:
RP23-193A16.4, 1110006G24Rik, Sk1, Spk1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8877

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-1969

--


Antigen:
JAK2

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Between 1082 and 1132

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-1972

--


Antigen:
TOPORS

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9NS56

Gene Symbols:
TOPORS

Immunogen:
Between 995 and 1045

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
TOPORS

Gene Alias:
LUN, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal domit), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, topoisomerase I-binding RING finger protein, TP53BPL, tumor suppressor p53-binding protein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10210

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-1974

--


Antigen:
TOPORS

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9NS56

Gene Symbols:
TOPORS

Immunogen:
Between 995 and 1045

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
TOPORS

Gene Alias:
LUN, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal domit), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, topoisomerase I-binding RING finger protein, TP53BPL, tumor suppressor p53-binding protein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10210

Content And Storage:
4° C

Form:
Liquid