50-156-27
CD278 (ICOS) Monoclonal Antibody (ISA-3), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-27-Each-of-1 | In Stock | ₹ 11,978.40 |
50-156-27 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,978.40
GST (18%): ₹ 2,156.112
Total Price: ₹ 14,134.512
Antigen
CD278 (ICOS)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9Y6W8
Gene Symbols
ICOS
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29851
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
ISA-3
Conjugate
PE-Cyanine7
Gene
ICOS
Gene Alias
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The ISA-3 monoclonal antibody reacts with human ICOS (Inducible COStimulatory molecule), also known as H4, CRP-1 and AILIM
- ICOS is a T cell specific activation molecule and a third member of the CD28/CTLA-4 family
- Human ICOS has a relative molecular mass of 55-60 kDa, composed of 27 kDa and 29 kDa chains
- Human ICOS on activated T cells has potent costimulatory activity for T cell activation and is required for humoral immune responses, in particular for memory B cell and plasma cell generation
- ICOS binds to its ligand, B7h/B7RP-1 expressed on activated APCs (antigen presenting cells) and on a number of inflamed peripheral tissues
- Plate-bound ISA-3 is costimulatory for T cells and induces production of IL-4, IL-5, IL-10 and other cytokines, but not IL-2
- ISA-3 has the same reactivity pattern and characteristics as F44
- ISA-3 was generated against the human ICOS antigen
- C398.4A, anti-mouse ICOS/H4 (catalog No
- 14-9949-82), was shown to cross-react with human ICOS but binds to an epitope different from ISA-3
- C398.4A stains activated cells brighter than ISA-3; however, it also exhibits higher staining of non-activated human peripheral blood or isolated PBMC
- To achieve the brightest staining of ICOS on activated human T cells, please use 13-9948-82 or 12-9948-42 rather than 11-9948-42
- Applications Reported: This ISA-3 antibody has been reported for use in flow cytometric analysis
- ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family
- It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation
- ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
Compare Similar Items
Show Difference
Antigen: CD278 (ICOS)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9Y6W8
Gene Symbols: ICOS
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29851
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: ISA-3
Conjugate: PE-Cyanine7
Gene: ICOS
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD278 (ICOS)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9Y6W8
Gene Symbols:
ICOS
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29851
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
ISA-3
Conjugate:
PE-Cyanine7
Gene:
ICOS
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CCDC86
Classification: Polyclonal
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9H6F5
Gene Symbols: CCDC86
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79080
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation
Clone: __
Conjugate: Unconjugated
Gene: CCDC86
Gene Alias: cyclon, cytokine-induced protein with coiled-coil domain, MGC2574
Host Species: Rabbit
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CCDC86
Classification:
Polyclonal
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9H6F5
Gene Symbols:
CCDC86
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79080
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Clone:
__
Conjugate:
Unconjugated
Gene:
CCDC86
Gene Alias:
cyclon, cytokine-induced protein with coiled-coil domain, MGC2574
Host Species:
Rabbit
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MIRK
Classification: Polyclonal
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9Y463
Gene Symbols: DYRK1B
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9149
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: DYRK1B
Gene Alias: DYRKB, Dual-specificity tyrosine-phosphorylation regulated kinase 1B, Mirk protein kinase
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MIRK
Classification:
Polyclonal
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9Y463
Gene Symbols:
DYRK1B
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9149
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
DYRK1B
Gene Alias:
DYRKB, Dual-specificity tyrosine-phosphorylation regulated kinase 1B, Mirk protein kinase
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CDC6
Classification: Polyclonal
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q99741
Gene Symbols: CDC6
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 990
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation
Clone: __
Conjugate: Unconjugated
Gene: CDC6
Gene Alias: Cyclin dependent kinase 6, CDC18L, HsCDC18, HsCDC6
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CDC6
Classification:
Polyclonal
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q99741
Gene Symbols:
CDC6
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
990
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation
Clone:
__
Conjugate:
Unconjugated
Gene:
CDC6
Gene Alias:
Cyclin dependent kinase 6, CDC18L, HsCDC18, HsCDC6
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG