50-156-28
CD278 (ICOS) Monoclonal Antibody (ISA-3), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-28-Each-of-1 | In Stock | ₹ 31,143.84 |
50-156-28 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,143.84
GST (18%): ₹ 5,605.891
Total Price: ₹ 36,749.731
Antigen
CD278 (ICOS)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9Y6W8
Gene Symbols
ICOS
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29851
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
ISA-3
Conjugate
PE-Cyanine7
Gene
ICOS
Gene Alias
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The ISA-3 monoclonal antibody reacts with human ICOS (Inducible COStimulatory molecule), also known as H4, CRP-1 and AILIM
- ICOS is a T cell specific activation molecule and a third member of the CD28/CTLA-4 family
- Human ICOS has a relative molecular mass of 55-60 kDa, composed of 27 kDa and 29 kDa chains
- Human ICOS on activated T cells has potent costimulatory activity for T cell activation and is required for humoral immune responses, in particular for memory B cell and plasma cell generation
- ICOS binds to its ligand, B7h/B7RP-1 expressed on activated APCs (antigen presenting cells) and on a number of inflamed peripheral tissues
- Plate-bound ISA-3 is costimulatory for T cells and induces production of IL-4, IL-5, IL-10 and other cytokines, but not IL-2
- ISA-3 has the same reactivity pattern and characteristics as F44
- ISA-3 was generated against the human ICOS antigen
- C398.4A, anti-mouse ICOS/H4 (catalog No
- 14-9949-82), was shown to cross-react with human ICOS but binds to an epitope different from ISA-3
- C398.4A stains activated cells brighter than ISA-3; however, it also exhibits higher staining of non-activated human peripheral blood or isolated PBMC
- To achieve the brightest staining of ICOS on activated human T cells, please use 13-9948-82 or 12-9948-42 rather than 11-9948-42
- Applications Reported: This ISA-3 antibody has been reported for use in flow cytometric analysis
- ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family
- It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation
- ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
Compare Similar Items
Show Difference
Antigen: CD278 (ICOS)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9Y6W8
Gene Symbols: ICOS
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29851
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: ISA-3
Conjugate: PE-Cyanine7
Gene: ICOS
Gene Alias: Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD278 (ICOS)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9Y6W8
Gene Symbols:
ICOS
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29851
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
ISA-3
Conjugate:
PE-Cyanine7
Gene:
ICOS
Gene Alias:
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: RECQ5
Classification: Polyclonal
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O94762
Gene Symbols: RECQL5
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9400
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: RECQL5
Gene Alias: DNA helicase, RecQ-like type 5, FLJ90603, RecQ helicase-like 5, RecQ protein 5, RecQ protein-like 5, RecQ5
Host Species: Rabbit
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RECQ5
Classification:
Polyclonal
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O94762
Gene Symbols:
RECQL5
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9400
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
RECQL5
Gene Alias:
DNA helicase, RecQ-like type 5, FLJ90603, RecQ helicase-like 5, RecQ protein 5, RecQ protein-like 5, RecQ5
Host Species:
Rabbit
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CBX2
Classification: Polyclonal
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q14781
Gene Symbols: CBX2
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84733
Content And Storage: 4° C
Form: Liquid
Applications: ChIP sequencing (ChIP-seq), Immunoprecipitation
Clone: __
Conjugate: Unconjugated
Gene: CBX2
Gene Alias: CDCA6, M33, SRXY5, Pc class homolog, cell division cycle associated 6, chromobox homolog 2 (Pc class homolog, Drosophila), chromobox protein homolog 2, modifier 3
Host Species: Rabbit
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CBX2
Classification:
Polyclonal
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q14781
Gene Symbols:
CBX2
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84733
Content And Storage:
4° C
Form:
Liquid
Applications:
ChIP sequencing (ChIP-seq), Immunoprecipitation
Clone:
__
Conjugate:
Unconjugated
Gene:
CBX2
Gene Alias:
CDCA6, M33, SRXY5, Pc class homolog, cell division cycle associated 6, chromobox homolog 2 (Pc class homolog, Drosophila), chromobox protein homolog 2, modifier 3
Host Species:
Rabbit
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CBX7
Classification: Polyclonal
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O95931
Gene Symbols: CBX7
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23492
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: CBX7
Gene Alias: chromobox protein homolog 7
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CBX7
Classification:
Polyclonal
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O95931
Gene Symbols:
CBX7
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23492
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
CBX7
Gene Alias:
chromobox protein homolog 7
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG