50-156-4062

TRPC6 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-4062-Each-of-1 In Stock ₹ 41,863.65

50-156-4062 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

TRPC6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRPC6

Gene Alias

Transient receptor potential Ca2+ channel 6A, trp6A, transient receptor potential cation channel, subfamily C, member 6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7225

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.2 mg/ml

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q9Y210

Gene Symbols

TRPC6

Immunogen

Between 350 and 400

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Trpc6 forms a receptor-activated calcium channel in the cell membrane
  • The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
  • Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
  • Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
  • Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family
  • The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
  • Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
  • When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
  • Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
  • There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
  • Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-156-4062

--


Antigen:
TRPC6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPC6

Gene Alias:
Transient receptor potential Ca2+ channel 6A, trp6A, transient receptor potential cation channel, subfamily C, member 6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7225

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9Y210

Gene Symbols:
TRPC6

Immunogen:
Between 350 and 400

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-4064

--


Antigen:
TRPC6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPC6

Gene Alias:
Transient receptor potential Ca2+ channel 6A, trp6A, transient receptor potential cation channel, subfamily C, member 6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7225

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9Y210

Gene Symbols:
TRPC6

Immunogen:
Between 350 and 400

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-4067

--


Antigen:
YTHDC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YTHDC2

Gene Alias:
CAHL, CsA-associated helicase-like protein, DKFZp564A186, FLJ10053, FLJ2194, YTH domain-containing protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64848

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9H6S0

Gene Symbols:
YTHDC2

Immunogen:
Between 1200 and 1250

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-4070

--


Antigen:
YTHDC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YTHDC2

Gene Alias:
CAHL, CsA-associated helicase-like protein, DKFZp564A186, FLJ10053, FLJ2194, YTH domain-containing protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64848

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9H6S0

Gene Symbols:
YTHDC2

Immunogen:
Between 1380 and 1430

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG