50-156-4064

TRPC6 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-4064-Each-of-1 In Stock ₹ 11,905.67

50-156-4064 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

TRPC6

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q9Y210

Gene Symbols

TRPC6

Immunogen

Between 350 and 400

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

TRPC6

Gene Alias

Transient receptor potential Ca2+ channel 6A, trp6A, transient receptor potential cation channel, subfamily C, member 6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7225

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Trpc6 forms a receptor-activated calcium channel in the cell membrane
  • The Trpc6 channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system
  • Activation of the Trpc6 channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium
  • Defects in the Trpc6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)
  • Further, Trpc6 is a member of the mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family
  • The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types
  • Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors
  • When expressed in transfected cells, Trpc6 acts as a non-selective store-independent receptor-activated cation channel
  • Trpc6 is activated by DAG in a PKC-independent manner and is insensitive to IP3 activation
  • There is increasing evidence that Trpc6 encodes endogenous DAG-activated receptor-operated cation channels in vivo
  • Diseases associated with TRPC6 include Glomerulosclerosis, Focal Segmental, 2 and Focal Segmental Glomerulosclerosis.

Compare Similar Items

Show Difference

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Bethyl Laboratories, Inc

50-156-4064

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Antigen:
TRPC6

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9Y210

Gene Symbols:
TRPC6

Immunogen:
Between 350 and 400

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TRPC6

Gene Alias:
Transient receptor potential Ca2+ channel 6A, trp6A, transient receptor potential cation channel, subfamily C, member 6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7225

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-4067

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Antigen:
YTHDC2

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9H6S0

Gene Symbols:
YTHDC2

Immunogen:
Between 1200 and 1250

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
YTHDC2

Gene Alias:
CAHL, CsA-associated helicase-like protein, DKFZp564A186, FLJ10053, FLJ2194, YTH domain-containing protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64848

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-4070

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Antigen:
YTHDC2

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9H6S0

Gene Symbols:
YTHDC2

Immunogen:
Between 1380 and 1430

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
YTHDC2

Gene Alias:
CAHL, CsA-associated helicase-like protein, DKFZp564A186, FLJ10053, FLJ2194, YTH domain-containing protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64848

Content And Storage:
4° C

Form:
Liquid

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Antigen:
DDX55

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q8NHQ9

Gene Symbols:
DDX55

Immunogen:
Between 175 and 225

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
DDX55

Gene Alias:
ATP-dependent RNA helicase DDX55, DEAD box protein 55, DDX55, KIAA1595

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57696

Content And Storage:
4° C

Form:
Liquid