50-156-6265
Cul4B Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-6265-Each-of-1 | In Stock | ₹ 41,863.65 |
50-156-6265 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
Cul4B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CUL4B
Gene Alias
MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
72584, 8450
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
A2A432, Q13620
Gene Symbols
CUL4B
Immunogen
Between 863 and 913
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
- The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
- CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
- Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
- Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
- Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
- Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
- Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8
- {ECO:0000269; PubMed:14578910, ECO:0000269; PubMed:16322693, ECO:0000269; PubMed:16678110, ECO:0000269; PubMed:18235224, ECO:0000269; PubMed:18593899, ECO:0000269; PubMed:19801544, ECO:0000269; PubMed:22118460}.
Compare Similar Items
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Antigen: Cul4B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUL4B
Gene Alias: MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 72584, 8450
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: A2A432, Q13620
Gene Symbols: CUL4B
Immunogen: Between 863 and 913
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Cul4B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUL4B
Gene Alias:
MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
72584, 8450
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
A2A432, Q13620
Gene Symbols:
CUL4B
Immunogen:
Between 863 and 913
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Cul4B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUL4B
Gene Alias: MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 72584, 8450
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: A2A432, Q13620
Gene Symbols: CUL4B
Immunogen: Between 863 and 913
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Cul4B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUL4B
Gene Alias:
MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
72584, 8450
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
A2A432, Q13620
Gene Symbols:
CUL4B
Immunogen:
Between 863 and 913
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ACL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACLY
Gene Alias: ACL, ATPCL, CLATP, ATP citrate synthase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, citrate cleavage enzyme
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 104112, 47
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: P53396, Q91V92
Gene Symbols: ACLY
Immunogen: Between 350 and 400
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ACL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACLY
Gene Alias:
ACL, ATPCL, CLATP, ATP citrate synthase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, citrate cleavage enzyme
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104112, 47
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
P53396, Q91V92
Gene Symbols:
ACLY
Immunogen:
Between 350 and 400
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NOP14
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOP14
Gene Alias: C4orf9, chromosome 4 open reading frame 9, NOL14, NOP14 homolog (S. cerevisiae), NOP14 nucleolar protein homolog, NOP14 nucleolar protein homolog (yeast), Nucleolar complex protein 14, nucleolar protein 14, nucleolar protein 14 homolog (yeast), probable nucleolar complex protein 14, RES425, RES4-25, UTP2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8602
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: P78316
Gene Symbols: NOP14
Immunogen: Between 50 and 100
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NOP14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOP14
Gene Alias:
C4orf9, chromosome 4 open reading frame 9, NOL14, NOP14 homolog (S. cerevisiae), NOP14 nucleolar protein homolog, NOP14 nucleolar protein homolog (yeast), Nucleolar complex protein 14, nucleolar protein 14, nucleolar protein 14 homolog (yeast), probable nucleolar complex protein 14, RES425, RES4-25, UTP2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8602
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
P78316
Gene Symbols:
NOP14
Immunogen:
Between 50 and 100
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG