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50-156-6267

Cul4B Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-156-6267-Each-of-1 In Stock ₹ 11,905.67

50-156-6267 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

Cul4B

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

A2A432, Q13620

Gene Symbols

CUL4B

Immunogen

Between 863 and 913

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

CUL4B

Gene Alias

MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

72584, 8450

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
  • CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
  • Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
  • Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
  • Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
  • Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8
  • {ECO:0000269; PubMed:14578910, ECO:0000269; PubMed:16322693, ECO:0000269; PubMed:16678110, ECO:0000269; PubMed:18235224, ECO:0000269; PubMed:18593899, ECO:0000269; PubMed:19801544, ECO:0000269; PubMed:22118460}.

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Show Difference

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Bethyl Laboratories, Inc

50-156-6267

--

Antigen:
Cul4B
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
A2A432, Q13620
Gene Symbols:
CUL4B
Immunogen:
Between 863 and 913
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
CUL4B
Gene Alias:
MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
72584, 8450
Content And Storage:
4° C
Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-6273

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Antigen:
ACL
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
P53396, Q91V92
Gene Symbols:
ACLY
Immunogen:
Between 350 and 400
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
ACLY
Gene Alias:
ACL, ATPCL, CLATP, ATP citrate synthase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, citrate cleavage enzyme
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104112, 47
Content And Storage:
4° C
Form:
Liquid

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Bethyl Laboratories, Inc

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Antigen:
NOP14
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
P78316
Gene Symbols:
NOP14
Immunogen:
Between 50 and 100
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
NOP14
Gene Alias:
C4orf9, chromosome 4 open reading frame 9, NOL14, NOP14 homolog (S. cerevisiae), NOP14 nucleolar protein homolog, NOP14 nucleolar protein homolog (yeast), Nucleolar complex protein 14, nucleolar protein 14, nucleolar protein 14 homolog (yeast), probable nucleolar complex protein 14, RES425, RES4-25, UTP2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8602
Content And Storage:
4° C
Form:
Liquid

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Bethyl Laboratories, Inc

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Antigen:
NOP14
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P78316, Q8R3N1
Gene Symbols:
NOP14
Immunogen:
Between 750 and 800
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
NOP14
Gene Alias:
C4orf9, chromosome 4 open reading frame 9, NOL14, NOP14 homolog (S. cerevisiae), NOP14 nucleolar protein homolog, NOP14 nucleolar protein homolog (yeast), Nucleolar complex protein 14, nucleolar protein 14, nucleolar protein 14 homolog (yeast), probable nucleolar complex protein 14, RES425, RES4-25, UTP2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
75416, 8602
Content And Storage:
4° C
Form:
Liquid