50-156-9844
DOK2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-9844-Each-of-1 | In Stock | ₹ 41,863.65 |
50-156-9844 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
DOK2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DOK2
Gene Alias
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9046
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
O60496
Gene Symbols
DOK2
Immunogen
Between 125 and 175
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Docking proteins interact with receptor tyrosine kinases and mediate particular biological responses using signal transduction
- Dok-2 acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases
- By this mechanism it acts to negatively regulate signal transduction and cell proliferation controlled by cytokines in a feedback loop
- Dok-2 is highly expressed in cells and tissues of hematopoietic origin as well as in lung
- Expression of bcr/abl induces additional tyrosine phosphorylation of the Dok1 and Dok2 proteins and their association with Ras-GAP
- Thus, it is suspected that DOK association regulates GAP activity toward Ras and that the Dok proteins serve as mediators of bcr-abl signaling
- The role of Dok proteins in bcr-abl regulation may also be implicated in chronic myelogenous leukemia (CML), which is characterized by a Philadelphia chromosome translocation t(9;22)
- Such a mutation would result in a p210-bcr/abl chimeric protein-tyrosine kinase which has been found in many CML cases.
Compare Similar Items
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Antigen: DOK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Between 125 and 175
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DOK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Between 125 and 175
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DOK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Between 125 and 175
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DOK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Between 125 and 175
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: APBA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APBA2
Gene Alias: D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 321
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q99767
Gene Symbols: APBA2
Immunogen: Between 275 and 325
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
APBA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APBA2
Gene Alias:
D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
321
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q99767
Gene Symbols:
APBA2
Immunogen:
Between 275 and 325
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ATG9A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATG9A
Gene Alias: Autophagy-related protein 9A, APG9-like 1, Cytoplasm to vacuole targeting protein 7, Autophagy-related protein 9, APG9A, APG9L1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79065
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q7Z3C6
Gene Symbols: ATG9A
Immunogen: Between 789 and 839
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATG9A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATG9A
Gene Alias:
Autophagy-related protein 9A, APG9-like 1, Cytoplasm to vacuole targeting protein 7, Autophagy-related protein 9, APG9A, APG9L1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79065
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q7Z3C6
Gene Symbols:
ATG9A
Immunogen:
Between 789 and 839
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG