50-156-9846
DOK2 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-9846-Each-of-1 | In Stock | ₹ 11,905.67 |
50-156-9846 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,905.67
GST (18%): ₹ 2,143.021
Total Price: ₹ 14,048.691
Antigen
DOK2
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
O60496
Gene Symbols
DOK2
Immunogen
Between 125 and 175
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
DOK2
Gene Alias
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9046
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Docking proteins interact with receptor tyrosine kinases and mediate particular biological responses using signal transduction
- Dok-2 acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases
- By this mechanism it acts to negatively regulate signal transduction and cell proliferation controlled by cytokines in a feedback loop
- Dok-2 is highly expressed in cells and tissues of hematopoietic origin as well as in lung
- Expression of bcr/abl induces additional tyrosine phosphorylation of the Dok1 and Dok2 proteins and their association with Ras-GAP
- Thus, it is suspected that DOK association regulates GAP activity toward Ras and that the Dok proteins serve as mediators of bcr-abl signaling
- The role of Dok proteins in bcr-abl regulation may also be implicated in chronic myelogenous leukemia (CML), which is characterized by a Philadelphia chromosome translocation t(9;22)
- Such a mutation would result in a p210-bcr/abl chimeric protein-tyrosine kinase which has been found in many CML cases.
Compare Similar Items
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Antigen: DOK2
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Between 125 and 175
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: 4° C
Form: Liquid
Antigen:
DOK2
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Between 125 and 175
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
4° C
Form:
Liquid
Antigen: APBA2
Classification: Polyclonal
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q99767
Gene Symbols: APBA2
Immunogen: Between 275 and 325
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation
Conjugate: Unconjugated
Gene: APBA2
Gene Alias: D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 321
Content And Storage: 4° C
Form: Liquid
Antigen:
APBA2
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q99767
Gene Symbols:
APBA2
Immunogen:
Between 275 and 325
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Gene:
APBA2
Gene Alias:
D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
321
Content And Storage:
4° C
Form:
Liquid
Antigen: ATG9A
Classification: Polyclonal
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q7Z3C6
Gene Symbols: ATG9A
Immunogen: Between 789 and 839
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: ATG9A
Gene Alias: Autophagy-related protein 9A, APG9-like 1, Cytoplasm to vacuole targeting protein 7, Autophagy-related protein 9, APG9A, APG9L1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79065
Content And Storage: 4° C
Form: Liquid
Antigen:
ATG9A
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q7Z3C6
Gene Symbols:
ATG9A
Immunogen:
Between 789 and 839
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
ATG9A
Gene Alias:
Autophagy-related protein 9A, APG9-like 1, Cytoplasm to vacuole targeting protein 7, Autophagy-related protein 9, APG9A, APG9L1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79065
Content And Storage:
4° C
Form:
Liquid
Antigen: ATG9A
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q7Z3C6
Gene Symbols: ATG9A
Immunogen: Between 789 and 839
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: ATG9A
Gene Alias: Autophagy-related protein 9A, APG9-like 1, Cytoplasm to vacuole targeting protein 7, Autophagy-related protein 9, APG9A, APG9L1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79065
Content And Storage: 4° C
Form: Liquid
Antigen:
ATG9A
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q7Z3C6
Gene Symbols:
ATG9A
Immunogen:
Between 789 and 839
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
ATG9A
Gene Alias:
Autophagy-related protein 9A, APG9-like 1, Cytoplasm to vacuole targeting protein 7, Autophagy-related protein 9, APG9A, APG9L1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79065
Content And Storage:
4° C
Form:
Liquid