50-156-9864

TMED10/TMP21 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-9864-Each-of-1 In Stock ₹ 11,905.67

50-156-9864 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

TMED10/TMP21

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

P49755, Q9D1D4

Gene Symbols

Tmed10

Immunogen

Between 50 and 100

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

TMED10

Gene Alias

Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10972, 68581

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Orangutan TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
  • More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
  • The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
  • Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer′s disease
  • Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
  • Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-156-9864

--


Antigen:
TMED10/TMP21

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P49755, Q9D1D4

Gene Symbols:
Tmed10

Immunogen:
Between 50 and 100

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TMED10

Gene Alias:
Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10972, 68581

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-9868

--


Antigen:
ACTR6

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9GZN1

Gene Symbols:
ACTR6

Immunogen:
Between 1 and 50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
ACTR6

Gene Alias:
ARP6, CDA12, FLJ13433, hARP6, hARPX, HSPC281, MSTP136

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64431

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-9874

--


Antigen:
ARHGAP4

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P98171

Gene Symbols:
ARHGAP4

Immunogen:
Between 700 and 750

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
ARHGAP4

Gene Alias:
C1, RGC1, RhoGAP4, SrGAP4, p115, Rho-GAP hematopoietic protein C1, rho GTPase-activating protein 4, rho-type GTPase-activating protein 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
393

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-9876

--


Antigen:
ARHGAP4

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P98171

Gene Symbols:
ARHGAP4

Immunogen:
Between 700 and 750

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
ARHGAP4

Gene Alias:
C1, RGC1, RhoGAP4, SrGAP4, p115, Rho-GAP hematopoietic protein C1, rho GTPase-activating protein 4, rho-type GTPase-activating protein 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
393

Content And Storage:
4° C

Form:
Liquid