50-156-9840
TMED10/TMP21 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-9840-Each-of-1 | In Stock | ₹ 11,905.67 |
50-156-9840 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,905.67
GST (18%): ₹ 2,143.021
Total Price: ₹ 14,048.691
Antigen
TMED10/TMP21
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
P49755, Q9D1D4
Gene Symbols
TMED10
Immunogen
Between 169 and 219
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
TMED10
Gene Alias
Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10972, 68581
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Rabbit, Golden hamster and Orangutan TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
- More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
- The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
- Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer′s disease
- Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
- Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
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Antigen: TMED10/TMP21
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: P49755, Q9D1D4
Gene Symbols: TMED10
Immunogen: Between 169 and 219
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: TMED10
Gene Alias: Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10972, 68581
Content And Storage: 4° C
Form: Liquid
Antigen:
TMED10/TMP21
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
P49755, Q9D1D4
Gene Symbols:
TMED10
Immunogen:
Between 169 and 219
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
TMED10
Gene Alias:
Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10972, 68581
Content And Storage:
4° C
Form:
Liquid
Antigen: APBA2
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q99767
Gene Symbols: APBA2
Immunogen: Between 125 and 175
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: APBA2
Gene Alias: D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 321
Content And Storage: 4° C
Form: Liquid
Antigen:
APBA2
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q99767
Gene Symbols:
APBA2
Immunogen:
Between 125 and 175
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
APBA2
Gene Alias:
D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L; X11-like protein; adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; mint-2; neuron-specific X11L protein; neuronal munc18-1-interacting protein 2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
321
Content And Storage:
4° C
Form:
Liquid
Antigen: DOK2
Classification: Polyclonal
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Between 125 and 175
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: 4° C
Form: Liquid
Antigen:
DOK2
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Between 125 and 175
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
4° C
Form:
Liquid
Antigen: DOK2
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O60496
Gene Symbols: DOK2
Immunogen: Between 125 and 175
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: DOK2
Gene Alias: p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9046
Content And Storage: 4° C
Form: Liquid
Antigen:
DOK2
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O60496
Gene Symbols:
DOK2
Immunogen:
Between 125 and 175
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
DOK2
Gene Alias:
p56(dok-2); Docking protein 2; Downstream of tyrosine kinase 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9046
Content And Storage:
4° C
Form:
Liquid