50-166-4154

PTPRC Mouse anti-Human, Clone: OTI3D8, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-4154-Each-of-1 In Stock ₹ 58,009.68

50-166-4154 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

PTPRC

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3D8

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

Full length human recombit protein of human PTPRC produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and maligt, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

Show Difference

Img

OriGene

50-166-4154

--


Antigen:
PTPRC

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3D8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Full length human recombit protein of human PTPRC produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4155

--


Antigen:
SYP

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SYP

Gene Alias:
MRX96, MRXSYP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6855

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI1A1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08247

Gene Symbols:
SYP

Immunogen:
Full length human recombit protein of human SYP produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4157

--


Antigen:
MAP2K1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MAP2K1

Gene Alias:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26395, 478347, 5604

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3E6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P31938, Q02750

Gene Symbols:
MAP2K1

Immunogen:
Full length human recombit protein of human MAP2K1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4159

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Antigen:
KLK8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
KLK8

Gene Alias:
HNP, NP, NRPN, PRSS19, TADG14

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11202

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5B1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O60259

Gene Symbols:
KLK8

Immunogen:
Full length human recombit protein of human KLK8 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1