50-166-4353

PTPRC Mouse anti-Human, Clone: OTI4C11, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-4353-Each-of-1 In Stock ₹ 58,009.68

50-166-4353 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

PTPRC

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4C11

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

Full length human recombit protein of human PTPRC produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and maligt, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

Show Difference

Img

OriGene

50-166-4353

--


Antigen:
PTPRC

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; HCD45

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4C11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Full length human recombit protein of human PTPRC produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-4354

--


Antigen:
TUBA1B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TUBA1B

Gene Alias:
K-ALPHA-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10376

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3H2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P68363

Gene Symbols:
TUBA1B

Immunogen:
Full length human recombit protein of human TUBA1B produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-4355

--


Antigen:
TUBA1B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TUBA1B

Gene Alias:
K-ALPHA-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10376

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3G3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P68363

Gene Symbols:
TUBA1B

Immunogen:
Full length human recombit protein of human TUBA1B produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-4357

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Antigen:
TGFB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TGFB1

Gene Alias:
CED, DPD1, LAP, TGFB, TGFbeta

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7040

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2B5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P01137

Gene Symbols:
TGFB1

Immunogen:
Full length human recombit protein of human TGFB1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a