50-166-6394

CEA (CEACAM5) Mouse anti-Human, Clone: OTI5F2, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-6394-Each-of-1 In Stock ₹ 60,342.00

50-166-6394 - Each of 1

₹ 60,342.00

In Stock

Quantity

1

Base Price: ₹ 60,342.00

GST (18%): ₹ 10,861.56

Total Price: ₹ 71,203.56

Antigen

CEA (CEACAM5)

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CEACAM5

Gene Alias

CD66e, CEA

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1048

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI5F2

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P06731

Gene Symbols

CEACAM5

Immunogen

Human recombit protein fragment corresponding to amino acids 35-680 of human CEACAM5 produced in SF9 cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CEA (Carcino Embryonic Antigen, CD66e) is synthesized during development in the fetal gut, and re-expressed in increased amounts in intestinal carcinomas and several other tumors
  • CEA is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3)
  • Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+)
  • CEA is a member of a large family of glycoproteins, a useful tumor marker for adenocarcinoma, and found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon
  • Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregcy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19
  • Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster
  • CEA was originally described in bile ducts of liver as biliary glycoprotein
  • Subsequently, CEA was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia
  • The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup
  • Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses
  • Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Compare Similar Items

Show Difference

Img

OriGene

50-166-6394

--


Antigen:
CEA (CEACAM5)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CEACAM5

Gene Alias:
CD66e, CEA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1048

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5F2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P06731

Gene Symbols:
CEACAM5

Immunogen:
Human recombit protein fragment corresponding to amino acids 35-680 of human CEACAM5 produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6396

--


Antigen:
NKX2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NKX2-1

Gene Alias:
BCH, BHC, NK-2, NKX2.1, NKX2A, NMTC1, T/EBP, TEBP, TITF1, TTF-1, TTF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7080

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI13H3

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P43699

Gene Symbols:
NKX2-1

Immunogen:
Full length human recombit protein of human NKX2-1 ( NP_003308) produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6397

--


Antigen:
CDH1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CDH1

Gene Alias:
Arc-1, BCDS1, CD324, CDHE, ECAD, LCAM, UVO

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
999

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3C11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P12830

Gene Symbols:
CDH1

Immunogen:
The extracellular domain of human CDH1 produced in human cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6399

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Antigen:
VWF

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VWF

Gene Alias:
F8VWF, VWD

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7450

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2D10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P04275

Gene Symbols:
VWF

Immunogen:
Human recombit protein fragment corresponding to amino acids 764-1263 of human VWF produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1