50-166-6483

CEA (CEACAM5) Mouse anti-Human, Clone: OTI1C2, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-166-6483-Each-of-1 In Stock ₹ 58,009.68

50-166-6483 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

CEA (CEACAM5)

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CEACAM5

Gene Alias

CD66e, CEA

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1048

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1C2

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P06731

Gene Symbols

CEACAM5

Immunogen

Human recombit protein fragment corresponding to amino acids 35-680 of human CEACAM5 produced in SF9 cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO CEA (Carcino Embryonic Antigen, CD66e) is synthesized during development in the fetal gut, and re-expressed in increased amounts in intestinal carcinomas and several other tumors
  • CEA is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3)
  • Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+)
  • CEA is a member of a large family of glycoproteins, a useful tumor marker for adenocarcinoma, and found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon
  • Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregcy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19
  • Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster
  • CEA was originally described in bile ducts of liver as biliary glycoprotein
  • Subsequently, CEA was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia
  • The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup
  • Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses
  • Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Compare Similar Items

Show Difference

Img

OriGene

50-166-6483

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Antigen:
CEA (CEACAM5)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CEACAM5

Gene Alias:
CD66e, CEA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1048

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P06731

Gene Symbols:
CEACAM5

Immunogen:
Human recombit protein fragment corresponding to amino acids 35-680 of human CEACAM5 produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

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OriGene

50-166-6484

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Antigen:
VEGF

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VEGFA

Gene Alias:
MVCD1, VEGF, VPF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7422

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2E11

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P15692

Gene Symbols:
VEGFA

Immunogen:
Human recombit protein fragment corresponding to amino acids 206-412 of human VEGFA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6486

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Antigen:
IL20

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IL20

Gene Alias:
IL-20, IL10D, ZCYTO10

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50604

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2B1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9NYY1

Gene Symbols:
IL20

Immunogen:
Human recombit protein fragment corresponding to amino acids 25-176 of human IL20 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

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Antigen:
SUPT4H1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SUPT4H1

Gene Alias:
SPT4, SPT4H, SUPT4H, Supt4a

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6827

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6B10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P63272

Gene Symbols:
SUPT4H1

Immunogen:
Full length human recombit protein of human SUPT4H1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1