50-166-6821

SETD2 Mouse anti-Human, Clone: OTI1B4, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-6821-Each-of-1 In Stock ₹ 58,009.68

50-166-6821 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

SETD2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

SETD2

Gene Alias

HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29072

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI1B4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q9BYW2

Gene Symbols

SETD2

Immunogen

Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-166-6799

--

Img

OriGene

50-166-6911

--

Img

OriGene

50-166-6957

--

Img

OriGene

50-166-7433

--

Img

OriGene

50-166-6695

--

Img

OriGene

50-166-7426

--

Img

OriGene

50-166-7034

--

Img

OriGene

50-166-7054

--

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Histone methyltransferase that specifically trimethylates ′Lys-36′ of histone H3 (H3K36me3) using dimethylated ′Lys-36′ (H3K36me2) as substrate
  • Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation
  • Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A
  • Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction
  • H3K36me3 also plays an essential role in the maintece of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A
  • H3K36me3 is also enhanced in intron-containing genes, suggesting that SETD2 recruitment is enhanced by splicing and that splicing is coupled to recruitment of elongating RNA polymerase
  • Required during angiogenesis
  • Recruited to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.

Compare Similar Items

Show Difference

Img

OriGene

50-166-6821

--


Antigen:
SETD2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SETD2

Gene Alias:
HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI1B4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9BYW2

Gene Symbols:
SETD2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6822

--


Antigen:
MTDH

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MTDH

Gene Alias:
3D3, AEG-1, AEG1, LYRIC, LYRIC/3D3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
92140

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2A6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q86UE4

Gene Symbols:
MTDH

Immunogen:
Human recombit protein fragment corresponding to amino acids 70-582 of human MTDH produced in SF9 cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-166-6823

--


Antigen:
KRT19

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
KRT19

Gene Alias:
CK19, K19, K1CS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3880

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1A8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P08727

Gene Symbols:
KRT19

Immunogen:
Human recombit protein fragment corresponding to amino acids 240-390 of human KRT19 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-6825

--


Antigen:
MAPKAPK5

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MAPKAPK5

Gene Alias:
MAPKAP-K5, MK-5, MK5, PRAK

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8550

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5E1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8IW41

Gene Symbols:
MAPKAPK5

Immunogen:
Human recombit protein fragment corresponding to amino acids 197-471 of human MAPKAPK5 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a