50-166-6911
SETD2 Mouse anti-Human, Clone: OTI3G8, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-6911-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-6911 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
SETD2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
SETD2
Gene Alias
HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29072
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Western Blot
Clone
OTI3G8
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
Q9BYW2
Gene Symbols
SETD2
Immunogen
Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO Histone methyltransferase that specifically trimethylates ′Lys-36′ of histone H3 (H3K36me3) using dimethylated ′Lys-36′ (H3K36me2) as substrate
- Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation
- Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A
- Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction
- H3K36me3 also plays an essential role in the maintece of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A
- H3K36me3 is also enhanced in intron-containing genes, suggesting that SETD2 recruitment is enhanced by splicing and that splicing is coupled to recruitment of elongating RNA polymerase
- Required during angiogenesis
- Recruited to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.
Compare Similar Items
Show Difference
Antigen: SETD2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: SETD2
Gene Alias: HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29072
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI3G8
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q9BYW2
Gene Symbols: SETD2
Immunogen: Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
SETD2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
SETD2
Gene Alias:
HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, p231HBP
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29072
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI3G8
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q9BYW2
Gene Symbols:
SETD2
Immunogen:
Human recombit protein fragment corresponding to amino acids 1787-2144 of human SETD2 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: TACC2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TACC2
Gene Alias: AZU-1, ECTACC
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10579
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI2D5
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O95359
Gene Symbols: TACC2
Immunogen: Human recombit protein fragment corresponding to amino acids 727-1026 of human TACC2 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
TACC2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TACC2
Gene Alias:
AZU-1, ECTACC
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10579
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI2D5
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O95359
Gene Symbols:
TACC2
Immunogen:
Human recombit protein fragment corresponding to amino acids 727-1026 of human TACC2 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: NAE1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: NAE1
Gene Alias: A-116A10.1, APPBP1, HPP1, ula-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8883
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI1A8
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q13564
Gene Symbols: NAE1
Immunogen: Human recombit protein fragment corresponding to amino acids 1-274 of human NAE1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
NAE1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
NAE1
Gene Alias:
A-116A10.1, APPBP1, HPP1, ula-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8883
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI1A8
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q13564
Gene Symbols:
NAE1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-274 of human NAE1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: UFD1L
Classification: Monoclonal
Conjugate: Unconjugated
Gene: UFD1
Gene Alias: UFD1L
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7353
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI3A12
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q92890
Gene Symbols: UFD1
Immunogen: Full length human recombit protein of human UFD1L produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG3
Antigen:
UFD1L
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
UFD1
Gene Alias:
UFD1L
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7353
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI3A12
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q92890
Gene Symbols:
UFD1
Immunogen:
Full length human recombit protein of human UFD1L produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3