50-166-8933
IRS1 Mouse anti-Human, Clone: OTI2B10, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-8933-Each-of-1 | In Stock | ₹ 60,342.00 |
50-166-8933 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,342.00
GST (18%): ₹ 10,861.56
Total Price: ₹ 71,203.56
Antigen
IRS1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
IRS1
Gene Alias
HIRS-1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3667
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2B10
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P35568
Gene Symbols
IRS1
Immunogen
Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
- IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
- An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
- Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
- Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
- IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.
Compare Similar Items
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Antigen: IRS1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: HIRS-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3667
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2B10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P35568
Gene Symbols: IRS1
Immunogen: Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
IRS1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
HIRS-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3667
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2B10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P35568
Gene Symbols:
IRS1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: IRS1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: HIRS-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3667
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI1D10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P35568
Gene Symbols: IRS1
Immunogen: Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
IRS1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
HIRS-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3667
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI1D10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P35568
Gene Symbols:
IRS1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: IRS1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: HIRS-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3667
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI3G10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: P35568
Gene Symbols: IRS1
Immunogen: Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
IRS1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
HIRS-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3667
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3G10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P35568
Gene Symbols:
IRS1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-280 of human IRS1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: LELP1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: LELP1
Gene Alias: late cornified envelope like proline rich 1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 149018
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI2B4
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q5T871
Gene Symbols: LELP1
Immunogen: Full length human recombit protein of human LELP1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
LELP1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
LELP1
Gene Alias:
late cornified envelope like proline rich 1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
149018
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI2B4
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q5T871
Gene Symbols:
LELP1
Immunogen:
Full length human recombit protein of human LELP1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1