50-166-9688

KLRB1 Mouse anti-Human, Clone: OTI1D8, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-9688-Each-of-1 In Stock ₹ 58,009.68

50-166-9688 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

KLRB1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

KLRB1

Gene Alias

CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3820

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1D8

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q12918

Gene Symbols

KLRB1

Immunogen

Human recombit protein fragment corresponding to amino acids 67-225 of human KLRB1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Related Products

Img

OriGene

50-166-9736

--

Img

OriGene

50-166-9802

--

Img

OriGene

50-167-0785

--

Img

OriGene

50-167-0875

--

Img

OriGene

50-166-9814

--

Img

OriGene

50-166-9817

--

Img

OriGene

50-167-0472

--

Img

OriGene

50-166-9924

--

Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO KLRB1 (Killer cell lectin like receptor subfamily B, member 1, CD-161) protein is classified as a type II membrane protein because it has an external C terminus
  • KLRB1 cell surface antigen is expressed by almost all NK cells and in a small subset of CD3+ve T cells
  • KLRB1 is a homodimeric cell surface protein, comprising two chains with molecular weights ranging from 40-44kDa
  • KLRB1 plays an inhibitory role on natural killer (NK) cells
  • Activation of KLRB1 leads to acid sphingomyelnase/SMPD1 stimulation and an increase in intracellular ceramide
  • Moreover, there is also an activation of AKT1/PKB and RPS6KA1/RSK1 kinase stimulation, and T cell proliferation by anti-CD3
  • KLRB1 acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope and to the N-acetyllactosamine epitope
  • KLRB1 also binds to CLEC2D/LLT1 as a ligand, and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells
  • The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain.

Compare Similar Items

Show Difference

Img

OriGene

50-166-9688

--


Antigen:
KLRB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
KLRB1

Gene Alias:
CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3820

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1D8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q12918

Gene Symbols:
KLRB1

Immunogen:
Human recombit protein fragment corresponding to amino acids 67-225 of human KLRB1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9689

--


Antigen:
TRIP13

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TRIP13

Gene Alias:
16E1BP, MVA3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9319

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2F5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q15645

Gene Symbols:
TRIP13

Immunogen:
Human recombit protein fragment corresponding to amino acids 31-148 of human TRIP13 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9690

--


Antigen:
TIMM8A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TIMM8A

Gene Alias:
DDP, DDP1, DFN1, MTS, TIM8

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1678

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5C8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O60220

Gene Symbols:
TIMM8A

Immunogen:
Full length human recombit protein of human TIMM8A produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-166-9691

--


Antigen:
MTA3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MTA3

Gene Alias:
metastasis associated 1 family member 3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57504

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2B8

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9BTC8

Gene Symbols:
MTA3

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-259 of human MTA3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1