50-166-9736
KLRB1 Mouse anti-Human, Clone: OTI5F10, lyophilized, TrueMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-9736-Each-of-1 | In Stock | ₹ 58,009.68 |
50-166-9736 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,009.68
GST (18%): ₹ 10,441.742
Total Price: ₹ 68,451.422
Antigen
KLRB1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
KLRB1
Gene Alias
CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3820
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Western Blot
Clone
OTI5F10
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
Q12918
Gene Symbols
KLRB1
Immunogen
Human recombit protein fragment corresponding to amino acids 67-225 of human KLRB1 produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO KLRB1 (Killer cell lectin like receptor subfamily B, member 1, CD-161) protein is classified as a type II membrane protein because it has an external C terminus
- KLRB1 cell surface antigen is expressed by almost all NK cells and in a small subset of CD3+ve T cells
- KLRB1 is a homodimeric cell surface protein, comprising two chains with molecular weights ranging from 40-44kDa
- KLRB1 plays an inhibitory role on natural killer (NK) cells
- Activation of KLRB1 leads to acid sphingomyelnase/SMPD1 stimulation and an increase in intracellular ceramide
- Moreover, there is also an activation of AKT1/PKB and RPS6KA1/RSK1 kinase stimulation, and T cell proliferation by anti-CD3
- KLRB1 acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope and to the N-acetyllactosamine epitope
- KLRB1 also binds to CLEC2D/LLT1 as a ligand, and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells
- The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain.
Compare Similar Items
Show Difference
Antigen: KLRB1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: KLRB1
Gene Alias: CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3820
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI5F10
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q12918
Gene Symbols: KLRB1
Immunogen: Human recombit protein fragment corresponding to amino acids 67-225 of human KLRB1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
KLRB1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
KLRB1
Gene Alias:
CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3820
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI5F10
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q12918
Gene Symbols:
KLRB1
Immunogen:
Human recombit protein fragment corresponding to amino acids 67-225 of human KLRB1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: SIRT1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: SIRT1
Gene Alias: SIR2, SIR2L1, SIR2alpha
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23411
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI1H1
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q96EB6
Gene Symbols: SIRT1
Immunogen: Human recombit protein fragment corresponding to amino acids 552-676 of human SIRT1 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
SIRT1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
SIRT1
Gene Alias:
SIR2, SIR2L1, SIR2alpha
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23411
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI1H1
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q96EB6
Gene Symbols:
SIRT1
Immunogen:
Human recombit protein fragment corresponding to amino acids 552-676 of human SIRT1 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: RGS13
Classification: Monoclonal
Conjugate: Unconjugated
Gene: RGS13
Gene Alias: regulator of G protein signaling 13
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6003
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Western Blot
Clone: OTI4G1
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: O14921
Gene Symbols: RGS13
Immunogen: Full length human recombit protein of human RGS13 produced in E.coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
RGS13
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
RGS13
Gene Alias:
regulator of G protein signaling 13
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6003
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Western Blot
Clone:
OTI4G1
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
O14921
Gene Symbols:
RGS13
Immunogen:
Full length human recombit protein of human RGS13 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: UPRT
Classification: Monoclonal
Conjugate: Unconjugated
Gene: UPRT
Gene Alias: FUR1, UPP
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 139596
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1D11
Formulation: PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.: Q96BW1
Gene Symbols: UPRT
Immunogen: Full length human recombit protein of human UPRT produced in 293T.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
UPRT
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
UPRT
Gene Alias:
FUR1, UPP
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
139596
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1D11
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
Q96BW1
Gene Symbols:
UPRT
Immunogen:
Full length human recombit protein of human UPRT produced in 293T.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1