50-167-0225

FOXO1 Mouse anti-Human, Clone: OTI2B5, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-0225-Each-of-1 In Stock ₹ 58,009.68

50-167-0225 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

FOXO1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

FOXO1

Gene Alias

FKH1, FKHR, FOXO1A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2308

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2B5

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q12778

Gene Symbols

FOXO1

Immunogen

Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
  • Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
  • Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
  • Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
  • FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
  • FOXO1 binds to the insulin response element (IRE) with consensus sequence 5′-TT[G/A]TTTTG-3′ and the related Daf-16 family binding element (DBE) with consensus sequence 5′- TT[G/A]TTTAC-3′
  • FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
  • Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
  • In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
  • FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0225

--


Antigen:
FOXO1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FOXO1

Gene Alias:
FKH1, FKHR, FOXO1A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2308

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2B5

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q12778

Gene Symbols:
FOXO1

Immunogen:
Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0227

--


Antigen:
NAT1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NAT1

Gene Alias:
AAC1, MNAT, NAT-1, NATI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4E9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P18440

Gene Symbols:
NAT1

Immunogen:
Full length human recombit protein of human NAT1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0228

--


Antigen:
VGLL1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VGLL1

Gene Alias:
TDU, VGL1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51442

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6E1

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q99990

Gene Symbols:
VGLL1

Immunogen:
Full length human recombit protein of human VGLL1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-167-0229

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Antigen:
DNAJB6

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DNAJB6

Gene Alias:
DJ4, DnaJ, HHDJ1, HSJ-2, HSJ2, LGMD1D, LGMD1E, MRJ, MSJ-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10049, 23950, 362293

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2F10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O54946, O75190, Q6AYU3

Gene Symbols:
Dnajb6

Immunogen:
Full length human recombit protein of human DNAJB6 produced in HEK293T.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1