50-167-0246

FOXO1 Mouse anti-Human, Clone: OTI2H4, lyophilized, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-0246-Each-of-1 In Stock ₹ 60,342.00

50-167-0246 - Each of 1

₹ 60,342.00

In Stock

Quantity

1

Base Price: ₹ 60,342.00

GST (18%): ₹ 10,861.56

Total Price: ₹ 71,203.56

Antigen

FOXO1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

FOXO1

Gene Alias

FKH1, FKHR, FOXO1A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2308

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Western Blot

Clone

OTI2H4

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

Q12778

Gene Symbols

FOXO1

Immunogen

Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
  • Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
  • Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
  • Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
  • FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
  • FOXO1 binds to the insulin response element (IRE) with consensus sequence 5′-TT[G/A]TTTTG-3′ and the related Daf-16 family binding element (DBE) with consensus sequence 5′- TT[G/A]TTTAC-3′
  • FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
  • Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
  • In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
  • FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0246

--


Antigen:
FOXO1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FOXO1

Gene Alias:
FKH1, FKHR, FOXO1A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2308

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2H4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q12778

Gene Symbols:
FOXO1

Immunogen:
Human recombit protein fragment corresponding to amino acids 356-655 of human FOXO1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0249

--


Antigen:
TNFRSF8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFRSF8

Gene Alias:
CD30, D1S166E, Ki-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI2H2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
Human recombit protein fragment corresponding to amino acids 408-595 of human TNFRSF8 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0251

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Antigen:
MYL1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MYL1

Gene Alias:
MLC1F, MLC3F

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4632

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1D9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P05976

Gene Symbols:
MYL1

Immunogen:
Human recombit protein fragment corresponding to amino acids 2-150 of human MYL1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0252

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Antigen:
TNFAIP8

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFAIP8

Gene Alias:
GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25816

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95379

Gene Symbols:
TNFAIP8

Immunogen:
Full length human recombit protein of human TNFAIP8 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1