50-167-0483

AIFM1 Mouse anti-Human, Mouse, Clone: OTI4E6, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-0483-Each-of-1 In Stock ₹ 58,009.68

50-167-0483 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

AIFM1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AIF, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26926, 9131

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4E6

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O95831, Q9Z0X1

Gene Symbols

AIFM1

Immunogen

Human recombit protein fragment corresponding to amino acids 134-483 of human AIFM1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0483

--


Antigen:
AIFM1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AIF, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26926, 9131

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4E6

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95831, Q9Z0X1

Gene Symbols:
AIFM1

Immunogen:
Human recombit protein fragment corresponding to amino acids 134-483 of human AIFM1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-167-0485

--


Antigen:
HHLA3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HHLA3

Gene Alias:
HERV-H LTR-associating 3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11147

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5D12

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9XRX5

Gene Symbols:
HHLA3

Immunogen:
Full length human recombit protein of human HHLA3 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0487

--


Antigen:
SOCS4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SOCS4

Gene Alias:
SOCS7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
122809

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI5H9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q8WXH5

Gene Symbols:
SOCS4

Immunogen:
Full length human recombit protein of human SOCS4 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-167-0489

--


Antigen:
CCNI

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CCNI

Gene Alias:
CCNI1, CYC1, CYI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10983

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI3F10

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q14094

Gene Symbols:
CCNI

Immunogen:
Human recombit protein fragment corresponding to amino acids 114-377 of human CCNI produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1