50-167-0509

AIFM1 Mouse anti-Human, Mouse, Clone: OTI5D2, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-0509-Each-of-1 In Stock ₹ 58,009.68

50-167-0509 - Each of 1

₹ 58,009.68

In Stock

Quantity

1

Base Price: ₹ 58,009.68

GST (18%): ₹ 10,441.742

Total Price: ₹ 68,451.422

Antigen

AIFM1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AIF, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26926, 9131

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI5D2

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

O95831, Q9Z0X1

Gene Symbols

AIFM1

Immunogen

Human recombit protein fragment corresponding to amino acids 134-483 of human AIFM1 produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

Compare Similar Items

Show Difference

Img

OriGene

50-167-0509

--


Antigen:
AIFM1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AIF, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26926, 9131

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5D2

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
O95831, Q9Z0X1

Gene Symbols:
AIFM1

Immunogen:
Human recombit protein fragment corresponding to amino acids 134-483 of human AIFM1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-167-0510

--


Antigen:
CAS9

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Cas9Cas9; Cas9

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI6D9

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-1166 of human CAS9 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-167-0513

--


Antigen:
ELF1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ELF1

Gene Alias:
EFTUD1, RIA1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1997

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4F4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P32519

Gene Symbols:
ELF1

Immunogen:
Full length human recombit protein of human ELF1 produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-167-0514

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Antigen:
NFIA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NFIA

Gene Alias:
BRMUTD, CTF, NF-I/A, NF1-A, NFI-A, NFI-L

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4774

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Clone:
OTI4G7

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q12857

Gene Symbols:
NFIA

Immunogen:
Human recombit protein fragment corresponding to amino acids 200-509 of human NFIA produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b