50-167-1360

Beta-catenin Mouse anti-Canine, Human, Clone: OTI1F3, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-1360-Each-of-1 In Stock ₹ 43,217.21

50-167-1360 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

Beta-catenin

Classification

Monoclonal

Conjugate

Unconjugated

Gene

CTNNB1

Gene Alias

CTNNB, EVR7, MRD19, armadillo

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1499, 477032

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1F3

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

B6V8E6, P35222

Gene Symbols

CTNNB1

Immunogen

Human recombit protein fragment corresponding to amino acids 531-781 of human beta-catenin produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
  • AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
  • Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
  • Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
  • The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
  • Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
  • A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
  • In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
  • The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

Compare Similar Items

Show Difference

Img

OriGene

50-167-1360

--


Antigen:
Beta-catenin

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
CTNNB, EVR7, MRD19, armadillo

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1499, 477032

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1F3

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
B6V8E6, P35222

Gene Symbols:
CTNNB1

Immunogen:
Human recombit protein fragment corresponding to amino acids 531-781 of human beta-catenin produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-167-1362

--


Antigen:
FOXA1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FOXA1

Gene Alias:
HNF3A, TCF3A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3169, 490657

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI3C1

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P55317

Gene Symbols:
FOXA1

Immunogen:
Full length human recombit protein of human FOXA1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-167-1363

--


Antigen:
CPA1 (Carboxypeptidase A1)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CPA1

Gene Alias:
CPA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1357

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A3

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P15085

Gene Symbols:
CPA1

Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 1-419 of human CPA-1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-167-1364

--


Antigen:
EpCAM

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EPCAM

Gene Alias:
DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI2G1

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16422

Gene Symbols:
EPCAM

Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 24-265 of human EpCAM

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1