50-167-1435
Beta-catenin Mouse anti-Canine, Human, Clone: OTI2D11, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-1435-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-1435 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
Beta-catenin
Classification
Monoclonal
Concentration
0.3 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
B6V8E6, P35222
Gene Symbols
CTNNB1
Immunogen
Human recombit protein fragment corresponding to amino acids 531-781 of human beta-catenin produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
OTI2D11
Conjugate
Unconjugated
Gene
CTNNB1
Gene Alias
CTNNB, EVR7, MRD19, armadillo
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1499, 477032
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
- AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
- Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
- Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
- The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
- Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
- A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
- In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
- The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.
Compare Similar Items
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Antigen: Beta-catenin
Classification: Monoclonal
Concentration: 0.3 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: B6V8E6, P35222
Gene Symbols: CTNNB1
Immunogen: Human recombit protein fragment corresponding to amino acids 531-781 of human beta-catenin produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI2D11
Conjugate: Unconjugated
Gene: CTNNB1
Gene Alias: CTNNB, EVR7, MRD19, armadillo
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1499, 477032
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Beta-catenin
Classification:
Monoclonal
Concentration:
0.3 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
B6V8E6, P35222
Gene Symbols:
CTNNB1
Immunogen:
Human recombit protein fragment corresponding to amino acids 531-781 of human beta-catenin produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI2D11
Conjugate:
Unconjugated
Gene:
CTNNB1
Gene Alias:
CTNNB, EVR7, MRD19, armadillo
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1499, 477032
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Cyp7b1
Classification: Monoclonal
Concentration: 0.63 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O75881
Gene Symbols: CYP7B1
Immunogen: Recombit protein expressed in E.coli corresponding to amino acids 350-506 of human Cyp7b1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Western Blot
Clone: OTI7H10
Conjugate: Unconjugated
Gene: CYP7B1
Gene Alias: CBAS3, CP7B, SPG5A
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9420
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Cyp7b1
Classification:
Monoclonal
Concentration:
0.63 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O75881
Gene Symbols:
CYP7B1
Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 350-506 of human Cyp7b1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Western Blot
Clone:
OTI7H10
Conjugate:
Unconjugated
Gene:
CYP7B1
Gene Alias:
CBAS3, CP7B, SPG5A
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9420
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CDX2
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q99626
Gene Symbols: CDX2
Immunogen: Recombit protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Western Blot
Clone: OTI3G4
Conjugate: Unconjugated
Gene: CDX2
Gene Alias: CDX-3, CDX2/AS, CDX3
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1045
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CDX2
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q99626
Gene Symbols:
CDX2
Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI3G4
Conjugate:
Unconjugated
Gene:
CDX2
Gene Alias:
CDX-3, CDX2/AS, CDX3
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1045
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TNNI3
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P19429
Gene Symbols: TNNI3
Immunogen: Recombit protein expressed in E.coli corresponding to amino acids 1-210 of human TNNI3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI3G2
Conjugate: Unconjugated
Gene: TNNI3
Gene Alias: CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7137
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TNNI3
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P19429
Gene Symbols:
TNNI3
Immunogen:
Recombit protein expressed in E.coli corresponding to amino acids 1-210 of human TNNI3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI3G2
Conjugate:
Unconjugated
Gene:
TNNI3
Gene Alias:
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7137
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid