50-167-1519
CHEK2 Mouse anti-Canine, Human, Clone: OTI4C10, liquid, TrueMAB™
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-1519-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-1519 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
CHEK2
Classification
Monoclonal
Concentration
1.88 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
O96017
Gene Symbols
CHEK2
Immunogen
Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
OTI4C10
Conjugate
Unconjugated
Gene
CHEK2
Gene Alias
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11200, 486338
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
- ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
- Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
- In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
- Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
- Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.
Compare Similar Items
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Antigen: CHEK2
Classification: Monoclonal
Concentration: 1.88 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O96017
Gene Symbols: CHEK2
Immunogen: Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: OTI4C10
Conjugate: Unconjugated
Gene: CHEK2
Gene Alias: CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11200, 486338
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CHEK2
Classification:
Monoclonal
Concentration:
1.88 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
OTI4C10
Conjugate:
Unconjugated
Gene:
CHEK2
Gene Alias:
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11200, 486338
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NTRK2
Classification: Monoclonal
Concentration: 1.17 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q16620
Gene Symbols: NTRK2
Immunogen: Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2E1
Conjugate: Unconjugated
Gene: NTRK2
Gene Alias: EIEE58, GP145-TrkB, OBHD, TRKB, trk-B
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4915
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NTRK2
Classification:
Monoclonal
Concentration:
1.17 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q16620
Gene Symbols:
NTRK2
Immunogen:
Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2E1
Conjugate:
Unconjugated
Gene:
NTRK2
Gene Alias:
EIEE58, GP145-TrkB, OBHD, TRKB, trk-B
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4915
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CHEK2
Classification: Monoclonal
Concentration: 0.98 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O96017
Gene Symbols: CHEK2
Immunogen: Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: OTI5C7
Conjugate: Unconjugated
Gene: CHEK2
Gene Alias: CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11200, 486338
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CHEK2
Classification:
Monoclonal
Concentration:
0.98 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
OTI5C7
Conjugate:
Unconjugated
Gene:
CHEK2
Gene Alias:
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11200, 486338
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PLK1
Classification: Monoclonal
Concentration: 0.96 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P53350
Gene Symbols: PLK1
Immunogen: Full-length protein expressed in 293T cell transfected with human PLK1 expression vector
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone: OTI8C12
Conjugate: Unconjugated
Gene: PLK1
Gene Alias: PLK, STPK13
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 489971, 5347
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PLK1
Classification:
Monoclonal
Concentration:
0.96 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P53350
Gene Symbols:
PLK1
Immunogen:
Full-length protein expressed in 293T cell transfected with human PLK1 expression vector
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
OTI8C12
Conjugate:
Unconjugated
Gene:
PLK1
Gene Alias:
PLK, STPK13
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
489971, 5347
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid