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50-167-1540

CHEK2 Mouse anti-Canine, Human, Rat, Clone: OTI2F4, liquid, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-1540-Each-of-1 In Stock ₹ 19,678.80

50-167-1540 - Each of 1

₹ 19,678.80

In Stock

Quantity

1

Base Price: ₹ 19,678.80

GST (18%): ₹ 3,542.184

Total Price: ₹ 23,220.984

Antigen

CHEK2

Classification

Monoclonal

Concentration

1.2 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O96017

Gene Symbols

CHEK2

Immunogen

Full length human recombit protein of human CHEK2 produced in HEK293T cell.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Rat

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot

Clone

OTI2F4

Conjugate

Unconjugated

Gene

CHEK2

Gene Alias

CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11200, 114212, 486338

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
  • ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
  • Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

Compare Similar Items

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Img

OriGene

50-167-1540

--

Antigen:
CHEK2
Classification:
Monoclonal
Concentration:
1.2 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O96017
Gene Symbols:
CHEK2
Immunogen:
Full length human recombit protein of human CHEK2 produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI2F4
Conjugate:
Unconjugated
Gene:
CHEK2
Gene Alias:
CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11200, 114212, 486338
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-1542

--

Antigen:
SSB
Classification:
Monoclonal
Concentration:
0.63 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P05455
Gene Symbols:
SSB
Immunogen:
Full-length protein expressed in 293T cell transfected with human SSB expression vector
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG3
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
OTI9D6
Conjugate:
Unconjugated
Gene:
SSB
Gene Alias:
LARP3, La, La/SSB
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
478787, 6741
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-1545

--

Antigen:
SSB
Classification:
Monoclonal
Concentration:
1.2 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P05455
Gene Symbols:
SSB
Immunogen:
Full-length protein expressed in 293T cell transfected with human SSB expression vector
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
OTI3H9
Conjugate:
Unconjugated
Gene:
SSB
Gene Alias:
LARP3, La, La/SSB
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
478787, 6741
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-1546

--

Antigen:
MAP2K4
Classification:
Monoclonal
Concentration:
1.09 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P45985
Gene Symbols:
MAP2K4
Immunogen:
Full-length protein expressed in 293T cell transfected with human MAP2K4 expression vector
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
OTI4B4
Conjugate:
Unconjugated
Gene:
MAP2K4
Gene Alias:
JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6416
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid