50-167-6221
ERBB2 Monoclonal Antibody (OTI4G7), TrueMAB™, OriGene
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-6221-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-6221 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
ERBB2
Classification
Monoclonal
Conjugate
Unconjugated
Gene
ERBB2
Gene Alias
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2064
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4G7
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P04626
Gene Symbols
ERBB2
Immunogen
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Related Products
Description
- ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
- ErbB2 has no ligand binding domain of its own and cannot bind growth factors
- However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
- Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
- Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
- In humans, the gene encoding ERBB2 is present on chromosome 17
- Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.
Compare Similar Items
Show Difference
Antigen: ERBB2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4G7
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
ERBB2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4G7
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: RFESD
Classification: Monoclonal
Conjugate: Unconjugated
Gene: RFESD
Gene Alias: Rieske Fe-S domain containing
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 317671
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI2A7
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q8TAC1
Gene Symbols: RFESD
Immunogen: Full length human recombit protein of human RFESD produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
RFESD
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
RFESD
Gene Alias:
Rieske Fe-S domain containing
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
317671
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI2A7
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q8TAC1
Gene Symbols:
RFESD
Immunogen:
Full length human recombit protein of human RFESD produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: BMP1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: BMP1
Gene Alias: OI13, PCOLC, PCP, PCP2, TLD
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 649
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: OTI3E9
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P13497
Gene Symbols: BMP1
Immunogen: Human recombit protein fragment corresponding to amino acids 225-617 of human BMP1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
BMP1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
BMP1
Gene Alias:
OI13, PCOLC, PCP, PCP2, TLD
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
649
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
OTI3E9
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P13497
Gene Symbols:
BMP1
Immunogen:
Human recombit protein fragment corresponding to amino acids 225-617 of human BMP1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: PIK3R5
Classification: Monoclonal
Conjugate: Unconjugated
Gene: PIK3R5
Gene Alias: F730038I15Rik, FOAP-2, P101-PI3K, p101
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23533, 320207, 497931, 612805
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI5B1
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q5SW28, Q8WYR1
Gene Symbols: PIK3R5
Immunogen: Full length human recombit protein of human PIK3R5 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Antigen:
PIK3R5
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
PIK3R5
Gene Alias:
F730038I15Rik, FOAP-2, P101-PI3K, p101
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23533, 320207, 497931, 612805
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI5B1
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q5SW28, Q8WYR1
Gene Symbols:
PIK3R5
Immunogen:
Full length human recombit protein of human PIK3R5 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a