50-167-6237
ERBB2 Monoclonal Antibody (OTI6H9), TrueMAB™, OriGene
Manufacturer: OriGene
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-6237-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-6237 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
ERBB2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P04626
Gene Symbols
ERBB2
Immunogen
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Western Blot
Clone
OTI6H9
Conjugate
Unconjugated
Gene
ERBB2
Gene Alias
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2064
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
- ErbB2 has no ligand binding domain of its own and cannot bind growth factors
- However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
- Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
- Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
- In humans, the gene encoding ERBB2 is present on chromosome 17
- Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.
Compare Similar Items
Show Difference
Antigen: ERBB2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Western Blot
Clone: OTI6H9
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI6H9
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NRAS
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P01111
Gene Symbols: NRAS
Immunogen: Full length human recombit protein of human NRAS produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI5G7
Conjugate: Unconjugated
Gene: NRAS
Gene Alias: ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4893
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NRAS
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P01111
Gene Symbols:
NRAS
Immunogen:
Full length human recombit protein of human NRAS produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI5G7
Conjugate:
Unconjugated
Gene:
NRAS
Gene Alias:
ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4893
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ERBB2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4F6
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4F6
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MAP2K3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O09110, P46734
Gene Symbols: MAP2K3
Immunogen: Full length human recombit protein of human MAP2K3 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI5F9
Conjugate: Unconjugated
Gene: MAP2K3
Gene Alias: MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26397, 303200, 489547, 5606
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MAP2K3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O09110, P46734
Gene Symbols:
MAP2K3
Immunogen:
Full length human recombit protein of human MAP2K3 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI5F9
Conjugate:
Unconjugated
Gene:
MAP2K3
Gene Alias:
MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26397, 303200, 489547, 5606
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid