50-167-6488

DDX58 Mouse anti-Human, Clone: OTI6C1, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-6488-Each-of-1 In Stock ₹ 19,678.80

50-167-6488 - Each of 1

₹ 19,678.80

In Stock

Quantity

1

Base Price: ₹ 19,678.80

GST (18%): ₹ 3,542.184

Total Price: ₹ 23,220.984

Antigen

DDX58

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

Full length human recombit protein of human DDX58 produced in HEK293T cell.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI6C1

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

RIG-I, RIGI, RLR-1, SGMRT2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

OriGene

50-167-6487

--

Img

OriGene

50-167-6537

--

Img

OriGene

50-167-6048

--

Img

OriGene

50-167-6430

--

Img

OriGene

50-167-6760

--

Img

OriGene

50-167-6819

--

Img

OriGene

50-167-6820

--

Img

OriGene

50-167-6824

--

Description

  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5′-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and ultimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

Img

OriGene

50-167-6488

--


Antigen:
DDX58

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
Full length human recombit protein of human DDX58 produced in HEK293T cell.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6C1

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
RIG-I, RIGI, RLR-1, SGMRT2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6489

--


Antigen:
CHGA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10645

Gene Symbols:
CHGA

Immunogen:
Full length human recombit protein of human CHGA produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2D6

Conjugate:
Unconjugated

Gene:
CHGA

Gene Alias:
CGA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1113

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6491

--


Antigen:
ENG

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P17813

Gene Symbols:
ENG

Immunogen:
Full length human recombit protein of human ENG produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3H5

Conjugate:
Unconjugated

Gene:
ENG

Gene Alias:
END, HHT1, ORW1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2022

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6494

--


Antigen:
ZSCAN21

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q07231, Q9Y5A6

Gene Symbols:
ZKSCAN1, Zscan21

Immunogen:
Full length human recombit protein of human ZSCAN21 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3B3

Conjugate:
Unconjugated

Gene:
ZSCAN21

Gene Alias:
NY-REN-21, ZNF38, Zipro1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22697, 489848, 7589

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid