50-167-6537

DDX58 Mouse anti-Human, Clone: OTI8D2, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-6537-Each-of-1 In Stock ₹ 43,217.21

50-167-6537 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

DDX58

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

Full length human recombit protein of human DDX58 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI8D2

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

RIG-I, RIGI, RLR-1, SGMRT2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5′-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and ultimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

Img

OriGene

50-167-6537

--


Antigen:
DDX58

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
Full length human recombit protein of human DDX58 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8D2

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
RIG-I, RIGI, RLR-1, SGMRT2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6538

--


Antigen:
NCAM1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P13591, P13595, P13596

Gene Symbols:
NCAM1

Immunogen:
Human recombit protein fragment corresponding to amino acids 20-718 of human NCAM1 produced in HEK293T cells.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1G4

Conjugate:
Unconjugated

Gene:
NCAM1

Gene Alias:
CD56, MSK39, NCAM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17967, 24586, 4684, 479435

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6541

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Antigen:
VHL

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P40337

Gene Symbols:
VHL

Immunogen:
Full length human recombit protein of human VHL produced in HEK293T cell.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E1

Conjugate:
Unconjugated

Gene:
VHL

Gene Alias:
HRCA1, RCA1, VHL1, pVHL

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7428

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-6544

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Antigen:
PDGFRB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P09619

Gene Symbols:
PDGFRB

Immunogen:
Full length human recombit protein of human PDGFRB (RNP_002600) produced in HEk293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
OTI1D1

Conjugate:
Unconjugated

Gene:
PDGFRB

Gene Alias:
CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5159

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid