50-167-7139

Beta-catenin Mouse anti-Canine, Human, Clone: OTI2H3, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-7139-Each-of-1 In Stock ₹ 44,280.72

50-167-7139 - Each of 1

₹ 44,280.72

In Stock

Quantity

1

Base Price: ₹ 44,280.72

GST (18%): ₹ 7,970.53

Total Price: ₹ 52,251.25

Antigen

Beta-catenin

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with <5% trehalose and 0.05% sodium azide

Gene Accession No.

B6V8E6, P35222

Gene Symbols

CTNNB1

Immunogen

Full length human recombit protein of human CTNNB1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA

Clone

OTI2H3

Conjugate

Unconjugated

Gene

CTNNB1

Gene Alias

CTNNB, EVR7, MRD19, armadillo

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1499, 477032

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
  • AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
  • Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
  • Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
  • The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
  • Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
  • A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
  • In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
  • The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

Compare Similar Items

Show Difference

Img

OriGene

50-167-7139

--


Antigen:
Beta-catenin

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <5% trehalose and 0.05% sodium azide

Gene Accession No.:
B6V8E6, P35222

Gene Symbols:
CTNNB1

Immunogen:
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA

Clone:
OTI2H3

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
CTNNB, EVR7, MRD19, armadillo

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1499, 477032

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-7140

--


Antigen:
CDCP1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <5% trehalose and 0.05% sodium azide

Gene Accession No.:
Q9H5V8

Gene Symbols:
CDCP1

Immunogen:
Full length human recombit protein of human CDCP1 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
OTI4G5

Conjugate:
Unconjugated

Gene:
CDCP1

Gene Alias:
CD318, SIMA135, TRASK

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64866

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-7142

--


Antigen:
CYP1A2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <5% trehalose and 0.05% sodium azide

Gene Accession No.:
P05177

Gene Symbols:
CYP1A2

Immunogen:
Full length human recombit protein of human CYP1A2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
OTI7A9

Conjugate:
Unconjugated

Gene:
CYP1A2

Gene Alias:
CP12, CYPIA2, P3-450, P450(PA)

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1544

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-7144

--


Antigen:
GFAP

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with <5% trehalose and 0.05% sodium azide

Gene Accession No.:
P14136

Gene Symbols:
GFAP

Immunogen:
Full length human recombit protein of human GFAP produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunoassay

Clone:
OTI5D7

Conjugate:
Unconjugated

Gene:
GFAP

Gene Alias:
ALXDRD

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2670

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid