50-167-7150
Beta-catenin Mouse anti-Human, Clone: OTI1B11, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-7150-Each-of-1 | In Stock | ₹ 44,280.72 |
50-167-7150 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,280.72
GST (18%): ₹ 7,970.53
Total Price: ₹ 52,251.25
Antigen
Beta-catenin
Clone
OTI1B11
Conjugate
Unconjugated
Gene
CTNNB1
Gene Alias
CTNNB, EVR7, MRD19, armadillo
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1499
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.
P35222
Gene Symbols
CTNNB1
Immunogen
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
- AJs are necessary for the creation and maintece of epithelial cell layers by regulating cell growth and adhesion between cells
- Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
- Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
- The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
- Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
- A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
- In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
- The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.
Compare Similar Items
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Antigen: Beta-catenin
Clone: OTI1B11
Conjugate: Unconjugated
Gene: CTNNB1
Gene Alias: CTNNB, EVR7, MRD19, armadillo
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1499
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.: P35222
Gene Symbols: CTNNB1
Immunogen: Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
Beta-catenin
Clone:
OTI1B11
Conjugate:
Unconjugated
Gene:
CTNNB1
Gene Alias:
CTNNB, EVR7, MRD19, armadillo
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1499
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.:
P35222
Gene Symbols:
CTNNB1
Immunogen:
Full length human recombit protein of human CTNNB1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: ACY1
Clone: OTI1E5
Conjugate: Unconjugated
Gene: ACY1
Gene Alias: ACY-1, ACY1D, HEL-S-5
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 95
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.: Q03154
Gene Symbols: ACY1
Immunogen: Full length human recombit protein of human ACY1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ACY1
Clone:
OTI1E5
Conjugate:
Unconjugated
Gene:
ACY1
Gene Alias:
ACY-1, ACY1D, HEL-S-5
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
95
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.:
Q03154
Gene Symbols:
ACY1
Immunogen:
Full length human recombit protein of human ACY1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: ACY1
Clone: OTI2B5
Conjugate: Unconjugated
Gene: ACY1
Gene Alias: ACY-1, ACY1D, HEL-S-5
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 95
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.: Q03154
Gene Symbols: ACY1
Immunogen: Full length human recombit protein of human ACY1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
ACY1
Clone:
OTI2B5
Conjugate:
Unconjugated
Gene:
ACY1
Gene Alias:
ACY-1, ACY1D, HEL-S-5
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
95
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.:
Q03154
Gene Symbols:
ACY1
Immunogen:
Full length human recombit protein of human ACY1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: MAPK1
Clone: OTI6F8
Conjugate: Unconjugated
Gene: MAPK1
Gene Alias: ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5594
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.: P28482
Gene Symbols: MAPK1
Immunogen: Full length human recombit protein of human MAPK1 produced in HEK293T cell.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
MAPK1
Clone:
OTI6F8
Conjugate:
Unconjugated
Gene:
MAPK1
Gene Alias:
ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5594
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.:
P28482
Gene Symbols:
MAPK1
Immunogen:
Full length human recombit protein of human MAPK1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1