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50-167-7954

CD20 (MS4A1) Mouse anti-Human, Biotin, Clone: OTI4A4, liquid, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-7954-Each-of-1 In Stock ₹ 47,761.30

50-167-7954 - Each of 1

₹ 47,761.30

In Stock

Quantity

1

Base Price: ₹ 47,761.30

GST (18%): ₹ 8,597.034

Total Price: ₹ 56,358.334

Antigen

CD20 (MS4A1)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P11836

Gene Symbols

MS4A1

Immunogen

Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunoassay

Clone

OTI4A4

Conjugate

Biotin

Gene

MS4A1

Gene Alias

B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

931

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most maligt B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell maligcies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

Compare Similar Items

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Img

OriGene

50-167-7954

--

Antigen:
CD20 (MS4A1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
MS4A1
Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunoassay
Clone:
OTI4A4
Conjugate:
Biotin
Gene:
MS4A1
Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-7955

--

Antigen:
CD20 (MS4A1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
MS4A1
Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
__
Clone:
OTI10A5
Conjugate:
Biotin
Gene:
MS4A1
Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-7956

--

Antigen:
CD20 (MS4A1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
MS4A1
Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
__
Clone:
OTI3C4
Conjugate:
Biotin
Gene:
MS4A1
Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-7957

--

Antigen:
BTK
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q06187
Gene Symbols:
BTK
Immunogen:
Full length human recombit protein of human BTK produced in HEK293T cell.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
__
Clone:
OTI12D4
Conjugate:
Biotin
Gene:
BTK
Gene Alias:
AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
695
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid