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50-167-8341

CD20 (MS4A1) Monoclonal Antibody (OTI1C12), TrueMAB™, OriGene

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-8341-Each-of-1 In Stock ₹ 43,217.21

50-167-8341 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CD20 (MS4A1)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P11836

Gene Symbols

MS4A1

Immunogen

Full length human recombit protein of human MS4A1 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1C12

Conjugate

Unconjugated

Gene

MS4A1

Gene Alias

B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

931

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most maligt B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell maligcies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

Compare Similar Items

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OriGene

50-167-8341

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Antigen:
CD20 (MS4A1)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
MS4A1
Immunogen:
Full length human recombit protein of human MS4A1 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI1C12
Conjugate:
Unconjugated
Gene:
MS4A1
Gene Alias:
B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-8342

--

Antigen:
BCL10
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O95999, Q9Z0H7
Gene Symbols:
BCL10
Immunogen:
Full length human recombit protein of human BCL10 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI3C4
Conjugate:
Unconjugated
Gene:
BCL10
Gene Alias:
CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12042, 8915
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-167-8343

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Antigen:
BCL10
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O95999
Gene Symbols:
BCL10
Immunogen:
Full length human recombit protein of human BCL10 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI1F11
Conjugate:
Unconjugated
Gene:
BCL10
Gene Alias:
CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8915
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

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OriGene

50-167-8344

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Antigen:
WDR74
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q6RFH5, Q8VCG3
Gene Symbols:
Wdr74
Immunogen:
Human recombit protein fragment corresponding to amino acids 114-385 of human WDR74 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4B2
Conjugate:
Unconjugated
Gene:
WDR74
Gene Alias:
WD repeat domain 74
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107071, 483778, 54663, 690229
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid