50-167-8468

CD2 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI1C5, liquid, TrueMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-167-8468-Each-of-1 In Stock ₹ 19,678.80

50-167-8468 - Each of 1

₹ 19,678.80

In Stock

Quantity

1

Base Price: ₹ 19,678.80

GST (18%): ₹ 3,542.184

Total Price: ₹ 23,220.984

Antigen

CD2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P06729, P08920, P08921

Gene Symbols

CD2

Immunogen

Full length human recombit protein of human CD2 produced in HEK293T cell.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1C5

Conjugate

Unconjugated

Gene

CD2

Gene Alias

LFA-2, SRBC, T11

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12481, 497761, 607448, 914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction betwee CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

OriGene

50-167-8468

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06729, P08920, P08921

Gene Symbols:
CD2

Immunogen:
Full length human recombit protein of human CD2 produced in HEK293T cell.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C5

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
LFA-2, SRBC, T11

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12481, 497761, 607448, 914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8469

--


Antigen:
TIA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P31483

Gene Symbols:
TIA1

Immunogen:
Full length human recombit protein of human TIA1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1A3

Conjugate:
Unconjugated

Gene:
TIA1

Gene Alias:
TIA-1, WDM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8470

--


Antigen:
TIA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P31483

Gene Symbols:
TIA1

Immunogen:
Full length human recombit protein of human TIA1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1D7

Conjugate:
Unconjugated

Gene:
TIA1

Gene Alias:
TIA-1, WDM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-8472

--


Antigen:
TIA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P31483

Gene Symbols:
TIA1

Immunogen:
Full length human recombit protein of human TIA1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C8

Conjugate:
Unconjugated

Gene:
TIA1

Gene Alias:
TIA-1, WDM

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid