50-167-9152
TNFRSF8 Monoclonal Antibody (OTI1G2), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-9152-Each-of-1 | In Stock | ₹ 43,217.21 |
50-167-9152 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
TNFRSF8
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P28908
Gene Symbols
TNFRSF8
Immunogen
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Western Blot
Clone
OTI1G2
Conjugate
Unconjugated
Gene
TNFRSF8
Gene Alias
CD30, D1S166E, Ki-1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
943
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- CD30 (Ki-1, TNF Receptor Superfamily Member 8) is a type I transmembrane glycoprotein of the TNF receptor superfamily
- CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1
- The ligand for CD30 is CD30L (CD153)
- The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
- CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas
- CD30 acts as a costimulatory molecule in thymic negative selection
- In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
- In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor
- Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response
- TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB
- CD30 is a positive regulator of apoptosis, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity
- Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
- CD30 is expressed by mononuclear cells in Hodgkin′s lymphoma, Reed Sternberg cells and most Anaplastic Large Cell Lymphomas (ALCL)
- CD30 is also expressed by embryonal carcinomas.
Compare Similar Items
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Antigen: TNFRSF8
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P28908
Gene Symbols: TNFRSF8
Immunogen: Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Western Blot
Clone: OTI1G2
Conjugate: Unconjugated
Gene: TNFRSF8
Gene Alias: CD30, D1S166E, Ki-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 943
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TNFRSF8
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Western Blot
Clone:
OTI1G2
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NUMB
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P49757
Gene Symbols: NUMB
Immunogen: Human recombit protein fragment corresponding to amino acids 1-365 of human NUMB produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Western Blot
Clone: OTI4D10
Conjugate: Unconjugated
Gene: NUMB
Gene Alias: C14orf41, S171, c14_5527
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8650
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NUMB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P49757
Gene Symbols:
NUMB
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-365 of human NUMB produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Western Blot
Clone:
OTI4D10
Conjugate:
Unconjugated
Gene:
NUMB
Gene Alias:
C14orf41, S171, c14_5527
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8650
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: DDIT3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P35638
Gene Symbols: DDIT3
Immunogen: Full length human recombit protein of human DDIT3 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2D3
Conjugate: Unconjugated
Gene: DDIT3
Gene Alias: C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1649
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DDIT3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P35638
Gene Symbols:
DDIT3
Immunogen:
Full length human recombit protein of human DDIT3 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2D3
Conjugate:
Unconjugated
Gene:
DDIT3
Gene Alias:
C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1649
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CD4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P01730
Gene Symbols: CD4
Immunogen: Full length human recombit protein of human CD4 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Western Blot
Clone: OTI4F10
Conjugate: Unconjugated
Gene: CD4
Gene Alias: CD4mut
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 920
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P01730
Gene Symbols:
CD4
Immunogen:
Full length human recombit protein of human CD4 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Western Blot
Clone:
OTI4F10
Conjugate:
Unconjugated
Gene:
CD4
Gene Alias:
CD4mut
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
920
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid