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50-168-0025

TNFRSF8 Monoclonal Antibody (OTI8D7), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-0025-Each-of-1 In Stock ₹ 43,217.21

50-168-0025 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

TNFRSF8

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P28908

Gene Symbols

TNFRSF8

Immunogen

Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry

Clone

OTI8D7

Conjugate

Unconjugated

Gene

TNFRSF8

Gene Alias

CD30, D1S166E, Ki-1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

943

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD30 (Ki-1, TNF Receptor Superfamily Member 8) is a type I transmembrane glycoprotein of the TNF receptor superfamily
  • CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1
  • The ligand for CD30 is CD30L (CD153)
  • The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
  • CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas
  • CD30 acts as a costimulatory molecule in thymic negative selection
  • In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
  • In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor
  • Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response
  • TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB
  • CD30 is a positive regulator of apoptosis, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity
  • Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
  • CD30 is expressed by mononuclear cells in Hodgkin′s lymphoma, Reed Sternberg cells and most Anaplastic Large Cell Lymphomas (ALCL)
  • CD30 is also expressed by embryonal carcinomas.

Compare Similar Items

Show Difference

Img

OriGene

50-168-0025

--

Antigen:
TNFRSF8
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
OTI8D7
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-0027

--

Antigen:
TNFRSF8
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 19-379 of human TNFRSF8 produced in E.coli
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
OTI1B2
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

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OriGene

50-168-0028

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Antigen:
CD34
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P28906
Gene Symbols:
CD34
Immunogen:
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Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry
Clone:
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Conjugate:
Unconjugated
Gene:
CD34
Gene Alias:
CD34 molecule
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
947
Content And Storage:
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OriGene

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Antigen:
ESR1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P03372
Gene Symbols:
ESR1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-310 of human ESR1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2D3
Conjugate:
Unconjugated
Gene:
ESR1
Gene Alias:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2099
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid