50-167-9767

MCAM Monoclonal Antibody (OTI1F10), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-9767-Each-of-1 In Stock ₹ 43,217.21

50-167-9767 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

MCAM

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P43121

Gene Symbols

MCAM

Immunogen

Full length human recombit protein of human MCAM produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1F10

Conjugate

Unconjugated

Gene

MCAM

Gene Alias

CD146, MUC18

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4162

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily
  • CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and maligt cell types
  • In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly
  • CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue
  • CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread
  • Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development
  • CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Compare Similar Items

Show Difference

Img

OriGene

50-167-9767

--


Antigen:
MCAM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P43121

Gene Symbols:
MCAM

Immunogen:
Full length human recombit protein of human MCAM produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1F10

Conjugate:
Unconjugated

Gene:
MCAM

Gene Alias:
CD146, MUC18

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9769

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Antigen:
RMND5A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H871

Gene Symbols:
RMND5A

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-249 of human RMND5A produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1B7

Conjugate:
Unconjugated

Gene:
RMND5A

Gene Alias:
CTLH, GID2, GID2A, RMD5, p44CTLH

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64795

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9770

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Antigen:
GBA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P04062

Gene Symbols:
GBA

Immunogen:
Human recombit protein fragment corresponding to amino acids 40-315 of human GBA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C12

Conjugate:
Unconjugated

Gene:
GBA

Gene Alias:
GBA1, GCB, GLUC

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2629

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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50-167-9772

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Antigen:
MSRB3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8IXL7

Gene Symbols:
MSRB3

Immunogen:
Human recombit protein fragment corresponding to amino acids 33-192 of human MSRB3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A2

Conjugate:
Unconjugated

Gene:
MSRB3

Gene Alias:
DFNB74

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
253827

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid