50-167-9726

MCAM Monoclonal Antibody (OTI2G10), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-9726-Each-of-1 In Stock ₹ 43,217.21

50-167-9726 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

MCAM

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P43121

Gene Symbols

MCAM

Immunogen

Full length human recombit protein of human MCAM produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2G10

Conjugate

Unconjugated

Gene

MCAM

Gene Alias

CD146, MUC18

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4162

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily
  • CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and maligt cell types
  • In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly
  • CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue
  • CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread
  • Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development
  • CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Compare Similar Items

Show Difference

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OriGene

50-167-9726

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Antigen:
MCAM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P43121

Gene Symbols:
MCAM

Immunogen:
Full length human recombit protein of human MCAM produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G10

Conjugate:
Unconjugated

Gene:
MCAM

Gene Alias:
CD146, MUC18

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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OriGene

50-167-9728

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Antigen:
ZNF286A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9HBT8

Gene Symbols:
ZNF286A

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-252 of human ZNF286A produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3C5

Conjugate:
Unconjugated

Gene:
ZNF286A

Gene Alias:
ZNF286

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57335

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Antigen:
MAP1LC3A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H492

Gene Symbols:
MAP1LC3A

Immunogen:
Full length human recombit protein of human MAP1LC3A produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2D5

Conjugate:
Unconjugated

Gene:
MAP1LC3A

Gene Alias:
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84557

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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OriGene

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Antigen:
MAP1LC3A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H492

Gene Symbols:
MAP1LC3A

Immunogen:
Full length human recombit protein of human MAP1LC3A produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4C5

Conjugate:
Unconjugated

Gene:
MAP1LC3A

Gene Alias:
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84557

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid