50-168-0505

PDGFRA Mouse anti-Human, Clone: OTI2E9, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-0505-Each-of-1 In Stock ₹ 43,217.21

50-168-0505 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PDGFRA

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PDGFRA

Gene Alias

CD140A, PDGFR-2, PDGFR2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5156

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

OTI2E9

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P16234

Gene Symbols

PDGFRA

Immunogen

Human recombit protein fragment corresponding to amino acids 32-324 of human PDGFRA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • PDGFRA (PDGFR-alpha, Platelet Derived Growth Factor Receptor alpha) belongs to the protein tyrosine kinase family, and binds to the alpha chain of PDGF
  • PDGFR exhibits two different isoforms, alpha and beta, which are coded by two different genes
  • PDGF-alpha receptors are expressed in oligodendrocyte progenitor cells while PDGF-beta receptors are expressed on neurons
  • PDGFR possess five immunoglobulin like domains that are involved in ligand binding
  • Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind
  • PDGF AA can bind and activate only PDGFR alpha, while PDGF BB can bind and activate both PDGFR alpha and beta
  • Members of the PDGF receptor subfamily are cell surface receptors that act as mitogens for cells of mesenchymal origin, and consist of alpha and beta isoforms of ∽190 and 125 kDa, respectively
  • Activated PDGF receptors act on signaling pathways that control cell growth, actin reorganization, migration, and differentiation
  • In humans, the gene is located on the q arm of chromosome 4
  • Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Compare Similar Items

Show Difference

Img

OriGene

50-168-0505

--


Antigen:
PDGFRA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDGFRA

Gene Alias:
CD140A, PDGFR-2, PDGFR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI2E9

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16234

Gene Symbols:
PDGFRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 32-324 of human PDGFRA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-0508

--


Antigen:
HDAC4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HDAC4

Gene Alias:
AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9759

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1E1

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P56524

Gene Symbols:
HDAC4

Immunogen:
Full length human recombit protein of human HDAC4 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-0524

--


Antigen:
UBA52

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
UBA52

Gene Alias:
CEP52, HUBCEP52, L40, RPL40

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7311

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI3C1

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P62987

Gene Symbols:
UBA52

Immunogen:
Human recombit protein fragment corresponding to amino acids 77-128 of human UBA52 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-0525

--


Antigen:
UBA52

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
UBA52

Gene Alias:
CEP52, HUBCEP52, L40, RPL40

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7311

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1C6

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P62987

Gene Symbols:
UBA52

Immunogen:
Human recombit protein fragment corresponding to amino acids 77-128 of human UBA52 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1